J Breast Cancer.  2011 Sep;14(3):237-240.

Borderline Phyllodes Tumor with an Incidental Invasive Tubular Carcinoma and Lobular Carcinoma In Situ Component: A Case Report

• Quinlan-Davidson S
• Hodgson N
• Elavathil
• Shangguo T

Abstract

Phyllodes tumors are an infrequent breast tumor presentation. A phyllodes tumor with a synchronous invasive ductal carcinoma is rarely described and has never been reported with lobular carcinoma in situ component. A 53-year-old female presented with a nine-year history of twice core biopsy proven fibroadenoma. After an increase in the tumor's growth velocity it was decided upon to undergo an excisional biopsy. Microscopic examination of the well-circumscribed pale-tan mass found focal areas of leaf like architecture with variable number of mitoses present, representing a phyllodes tumor of borderline malignant potential. Incidentally, at one edge of the mass was found a tubular carcinoma and lobular carcinoma in situ components. Thorough, routine follow-up of patients with biopsy proven benign breast masses is important to finding a masked malignant component.

Keyword

Breast neoplasms; Breast screening; Fibroepithelial tumor; Mammography

MeSH Terms

Adenocarcinoma
Biopsy
Breast
Breast Neoplasms
Carcinoma, Ductal
Carcinoma, Lobular
Female
Fibroadenoma
Follow-Up Studies
Humans
Mammography
Masks
Middle Aged
Mitosis
Phyllodes Tumor