Obstet Gynecol Sci.  2017 Sep;60(5):469-472. 10.5468/ogs.2017.60.5.469.

Epithelial ovarian tumors in a premenarchal girl: a rare case report

• Ojha P
• Nigam JS
• Deshpande
• Gargade CB

• KMID: 2393847
• DOI: http://doi.org/10.5468/ogs.2017.60.5.469

Abstract

Ovarian tumors are relatively uncommon in paediatric age group and mostly occur in the period after menarche and are extremely rare prior to menarche. However, in children and adolescent, the epithelial ovarian tumors account approximately 10% to 28% of all ovarian tumors. In the present case, the patient was presented with abdominal pain for 1 day and no mass was felt on physical examination. Contrast-enhance computed tomography abdomen and pelvis showed a left ovarian cystic mass measuring 7.3×5.1 cm in size and unilateral oophorectomy was done. Tumor shows multiloculated cysts of varying sizes filled with mucinous fluid. Cysts were lined by tall columnar epithelial cells and show predominantly periodic acid-Schiff positive neutral mucin favouring benign nature of lesion. We present this case due to its uncommon age of presentation and the patient was premenarchal girl.

Keyword

Ovarian neoplasm; Glandular neoplasm; Periodic acid-Schiff reaction; Alcian blue; Fertility

MeSH Terms

Abdomen
Abdominal Pain
Adolescent
Alcian Blue
Child
Epithelial Cells
Female*
Fertility
Humans
Menarche
Mucins
Neoplasms, Glandular and Epithelial
Ovarian Cysts
Ovarian Neoplasms
Ovariectomy
Pelvis
Periodic Acid-Schiff Reaction
Physical Examination
Alcian Blue
Mucins

Figure

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  Fig. 1 (A) Contrast enhance computed tomography (CECT): hypodense cystic tumor with enhancing septations. (B) Ovarian cyst with smooth external surface. (C) Cut surface: multilocular cyst.

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  Fig. 2 (A) Mucinous endocervical type epithelium (H&E, ×10, ×40 inset). (B) Mucinous endocervical-type epithelium with basally located nuclei (H&E, ×40). (C) Ovarian stroma with graafian follicles (H&E, ×40). (D) Mucinous epithelium with calcification (H&E, ×40). (E) Diastase resistant periodic acid-Schiff (PAS) positivity in lining epithelium (PAS-diastase, ×40). (F) PAS positive alcian blue negative in lining epithelium (Alcian blue-PAS, ×40).

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