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A Global Survey of Reproductive Specialists to Determine the Clinical Utility of Oxidative Stress Testing and Antioxidant Use in Male Infertility

Agarwal A, Finelli R, Selvam MKP, Leisegang K, Majzoub A, Tadros N, Ko E, Parekh N, Henkel R, Durairajanayagam D, Colpi GM, Cho CL, Sallam HN, Park HJ, Saleh R, Micic S, Ambar RF, Zini A, Tremellen K, Alvarez JG, Palani A, Arafa M, Gava MM, Jindal S, Amar E, Kopa Z, Moein MR, Busetto GM, Sengupta P, Kavoussi P, Maldonado I, Fikri J, Borges Jr. E, Martinez M, Bojovic D, Rajmil O, Aydos K, Parekattil S, Marmar JL, Sefrioui O, Jungwirth A, Rodriguez Peña MG, Cordts EB, Elbardisi H, Mostafa T, Sabbaghian M, Gilani MAS, Morimoto Y, Alves MG, Spasic A, Kenic U, Ramsay J, Akande EO, Oumeziane A, Dozortsev D, Chung E, Bell E, Allegra A, Tanos V, Fiadjoe M, Gurgan T, Michel AA, Hazem AR, Oborna I, Arab H, Esteves S, Amer M, Kadioglu A, Yuzko O, Korsak V, Shah R

Purpose: The use of antioxidants is common practice in the management of infertile patients. However, there are no established guidelines by professional societies on antioxidant use for male infertility. Materials and...
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Evaluation of SARS-CoV-2 in Human Semen and Effect on Total Sperm Number: A Prospective Observational Study

Best JC, Kuchakulla M, Khodamoradi K, Lima TFN, Frech FS, Achua J, Rosete O, Mora B, Arora H, Ibrahim E, Ramasamy R

Purpose: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has created a surge of research to help better understand the breadth of possible sequelae. However, little is known regarding...
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The Use of Testicular Sperm for Intracytoplasmic Sperm Injection in Patients with High Sperm DNA Damage: A Systematic Review

Ambar RF, Agarwal A, Majzoub A, Vij S, Tadros NN, Cho CL, Parekh N, Borges Jr. E, Glina S

The advent of intracytoplasmic sperm injection (ICSI) has changed the human reproduction landscape by overcoming several limitations related to both male and female infertility factors. However, despite the development of...
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Practical issues and research trends of oncofertility in gynecologic cancer

Park JY

In recent years, there has been a greater impetus toward preserving fertility in young women with gynecologic cancer. This is related to the increasing incidence of gynecologic cancer in young...
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Successful pregnancy following transmyometrial embryo transfer after robot-assisted radical trachelectomy

Hue HJ, Choi HJ, Park JY, Suh DH, Lee JR, Jee BC, Kim SK

Radical trachelectomy is a fertility-preserving alternative to radical hysterectomy in carefully selected young women with early-stage cervical cancer. However, in cases with subsequent severe cervical stenosis, assisted reproductive techniques can...
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Influence of hydrogel encapsulation during cryopreservation of ovarian tissues and impact of post-thawing in vitro culture systems in a research animal model

Thuwanut P, Comizzoli P, Pimpin A, Srituravanich W, Sereepapong W, Pruksananonda K, Taweepolcharoen C, Tuntiviriyapun P, Suebthawinkul C, Sirayapiwat P

Objective: Using domestic cats as a biomedical research model for fertility preservation, the present study aimed to characterize the influences of ovarian tissue encapsulation in biodegradable hydrogel matrix (fibrinogen/thrombin) on...
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Effect of phosphodiesterase type 5 inhibitors on sperm motility and acrosome reaction: An in vitro study

Song SH, Shin DH, Her YS, Oh MH, Baek JW, Sung S, Eum JH, Heo Y, Kim DS

Purpose: Phosphodiesterase type 5 (PDE5) inhibitors are effective treatments for erectile dysfunction, and several recent studies have reported positive effects of PDE5 inhibitors on semen parameters as well. However, the...
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Assessment of different NEoplasias in the adneXa model for differentiation of benign and malignant adnexal masses in Korean women

Nam G, Lee SR, Jeong K, Kim SH, Moon HS, Chae HD

Objective Ultrasonographic differential diagnosis of ovarian tumors is important for appropriate management. We conducted study to compare the performance of the Assessment of Different NEoplasias in the adneXa (ADNEX) model...
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Physical Activity and Successful Pregnancy in 6 Months: A Finding from the Pregnancy and Urban Environment Study

An SM, Choe SA, Jun B

Purpose: This study aimed to assess the association between physical activity and pregnancy in 6 months among infertile women who underwent in vitro fertilization (IVF). Methods: The participants included in this...
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A Novel Approach to Improving the Reliability of Manual Semen Analysis: A Paradigm Shift in the Workup of Infertile Men

Douglas C, Parekh N, Kahn LG, Henkel R, Agarwal A

Conventional semen analysis (SA) is an essential component of the male infertility workup, but requires laboratories to rigorously train and monitor technicians as well as regularly perform quality assurance assessments....
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The role of gonadotropin-releasing hormone agonists in female fertility preservation

Lee JH, Choi YS

Advances in anticancer treatments have resulted in increasing survival rates among cancer patients. Accordingly, the quality of life after treatment, particularly the preservation of fertility, has gradually emerged as an...
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Controlled ovarian hyperstimulation for fertility preservation in women with breast cancer: Practical issues

Park SY, Jeong K, Cho EH, Chung HW

In Korean women, a westernized lifestyle is associated with an increased risk of breast cancer. Fertility preservation has become an increasingly important issue for women with breast cancer, in accordance...
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Fertility-sparing treatment for intramucous, moderately differentiated, endometrioid endometrial cancer: a Gynecologic Cancer Inter-Group (GCIG) study

Falcone F, Maggiore ULR, Donato VD, Perrone AM, Frigerio L, Bifulco G, Polterauer S, Casadio P, Cormio G, Masciullo V, Malzoni M, Greggi S

Objective: ‘The Endometrial Cancer Conservative Treatment (E.C.Co.). A multicentre archive’ is a worldwide project endorsed by the Gynecologic Cancer Inter-Group, aimed at registering conservatively treated endometrial cancer (EC) patients. This...
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Comparison of the deleterious effects of yaji and cadmium chloride on testicular physiomorphological and oxidative stress status: The gonadoprotective effects of an omega-3 fatty acid

Ekhoye EI, Olerimi SE, Ehebha SE

Objective This study investigated testicular oxidative stress status and physiomorphological function in Wistar rats fed with yaji and cadmium chloride (CdCl2). Methods: Sixty male albino Wistar rats (12 per group) were...
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Exploring Reproductive Health Education Needs in Infertile Women in Iran: A Qualitative Study

Khakbazan Z, Maasoumi R, Rakhshaee Z, Nedjat S

Objectives: An inadequate understanding of infertility can affect individuals’ self-efficacy and ability to perform self-care; thus, reproductive health education is an important part of infertility treatment. The present qualitative study...
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Comparison of Clinical Pregnancy Rates and Affecting Factors Between Elderly and Young Infertile Females After Intra-Uterine Insemination: Benefited by ‘National Medical-aid Program for ART (assisted reproductive technology) in 2016

Jang I, Kim D, Kim JS

Purpose: The purpose of this study was to evaluate the intrauterine insemination (IUI) success rate and to define the variables for predicting success. Methods: The secondary data analysis was used...
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Attitudes towards Parenthood and Fertility Awareness in Female and Male University Students in South Korea

Shin H, Lee J, Kim SJ, Jo M

Purpose: This study investigated intentions and attitudes towards future parenthood and awareness of fertility among university students in South Korea. Methods: The participants comprised 166 female and male undergraduate students enrolled...
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Knowledge and awareness about fertility preservation among female patients with cancer : a cross-sectional study

Mahey R, Kandpal S, Gupta M, Vanamail P, Bhatla N, Malhotra N

Objective The incidence of women in the reproductive age group diagnosed with cancer has recently increased. However, very few patients opt for or are offered fertility preservation (FP) strategies because...
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Fertility-sparing treatment in early endometrial cancer: current state and future strategies

Obermair A, Baxter E, Brennan DJ, McAlpine JN, Muellerer JJ, Amant F, van Gent MDJM, Coleman RL, Westin SN, Yates MS, Krakstad C, Janda M

Endometrial cancer (EC) is the fifth most common cancer in women worldwide. Global estimates show rising incidence rates in both developed and developing countries. Most women are diagnosed postmenopausal, but...
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Clinical correlation among male infertility and overall male health: A systematic review of the literature

Giudice FD, Kasman AM, Ferro M, Sciarra A, Berardinis ED, Belladelli F, Salonia A, Eisenberg ML

Purpose: Ongoing evidence has suggested the role of male factor infertility as a potential predictor of mortality and general health status. The aim of the present review is to update...
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