J Gastric Cancer.  2015 Dec;15(4):256-261. 10.5230/jgc.2015.15.4.256.

Effect of Carrot Intake in the Prevention of Gastric Cancer: A Meta-Analysis

• Fallahzadeh H
• Jalali A
• Momayyezi
• Bazm S

• KMID: 2391560
• DOI: http://doi.org/10.5230/jgc.2015.15.4.256

Abstract

PURPOSE
Gastric cancer is the third leading cause of cancer-related mortality, with the incidence and mortality being higher in men than in women. Various studies have shown that eating carrots may play a major role in the prevention of gastric cancer. We conducted a meta-analysis to determine the relationship between carrot consumption and gastric cancer.
MATERIALS AND METHODS
We searched multiple databases including PubMed, Cochrane Library, Scopus, ScienceDirect, and Persian databases like Scientific Information Database (SID) and IranMedx. The following search terms were used: stomach or gastric, neoplasm or cancer, carcinoma or tumor, and carrot. Statistical analyses were performed using Comprehensive Meta Analysis/2.0 software.
RESULTS
We retrieved 81 articles by searching the databases. After considering the inclusion and exclusion criteria, 5 articles were included in this study. The odds ratio (OR) obtained by fixed effects model showed that a 26% reduction in the risk of gastric cancer has been associated with the consumption of carrots) OR=0.74; 95% confidence interval=0.68~0.81; P<0.0001). According to funnel graph, the results showed that the possibility of a publication bias does not exist in this study.
CONCLUSIONS
The findings of this study showed an inverse relationship between the consumption of carrots and the risk of gastric cancer.

Keyword

Stomach; Neoplasm; Carcinoma; Daucus carota

MeSH Terms

Daucus carota*
Eating
Female
Humans
Incidence
Male
Mortality
Odds Ratio
Publication Bias
Stomach
Stomach Neoplasms*

Figure

• 

  Fig. 1 Flow chart of study selection.

• 

  Fig. 2 Forest plot of relationship between the consumption of carrots and gastric cancer. Blank = the absence of subgroups in the study; FHGC- = No family history of gastric cancer; FHGC+ = family history of gastric cancer; CI = confidence interval.

• 

  Fig. 3 Funnel plot of relationship between the consumption of carrots and gastric cancer.

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