J Pathol Transl Med.  2015 May;49(3):270-273. 10.4132/jptm.2015.04.01.

Cytomegalovirus-Associated Intussusception with Florid Vascular Proliferation in an Infant

Affiliations
  • 1Department of Pathology, National Health Insurance Service Ilsan Hospital, Goyang, Korea.
  • 2Department of Pathology, Ewha Womans University School of Medicine, Seoul, Korea. mcho1124@ewha.ac.kr
  • 3Department of Surgery, Ewha Womans University School of Medicine, Seoul, Korea.
  • 4Department of Radiology, Ewha Womans University School of Medicine, Seoul, Korea.

Abstract

No abstract available.


MeSH Terms

Humans
Infant*
Intussusception*

Figure

  • Fig. 1. (A) Longitudinal ultrasonography of the lower abdomen with a Doppler study shows an ovoid mass with alternating thick hypoechoic and thin hyperechoic layers, indicating ileoileal intussusception and Doppler flow signals at the intussusceptum. A round hypoechoic lesion (arrow) indicating a lead point of intussusception is identified. (B) The ileum reveals a 4×2×1 cm, roughly ovoid, sessile, polypoid mass with a conglomerated nodular or nodule-aggregating appearance. (C) The cut surface shows thickened mucosa and multiple round solid nodules with focal hemorrhages at deeper layers. (D) The polyp is composed of enlarged plicae circulares having dilated and distorted crypt glands with expanded lamina propria.

  • Fig. 2. (A) The lamina propria shows granulation tissue-type small vessel proliferation. (B) The nodules at deeper layers are composed of proliferated florid small vessels and fibroblasts. (C) Organizing-thrombus-like areas are noted focally in the nodules. (D) A few stromal cells with intranuclear and cytoplasmic cytomegalovirus inclusions are present beneath the eroded mucosal surface.


Reference

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