Yeungnam Univ J Med.  1989 Jun;6(1):109-119. 10.12701/yujm.1989.6.1.109.

Serum Angiotensin-Coverting Enzyme Levels in Coal Worker's Pneumoconiosis

• Kim KD
• Choi MS
• Lee CH
• Kim CS
• Bae EK

• KMID: 2377267
• DOI: http://doi.org/10.12701/yujm.1989.6.1.109

Abstract

We measured fasting Serum Angiotensin-Converting Enzyme (SACE) in 100 healthy controls and 75 coal worker's pneumoconiosis (CWP) patients by a commercial kits (ACEcolor®, Fujirio Inc., Japan) and evaluated this manual method. The linear range extends to an activity of 80U/L. Precision on a commercial control serum (ACE control-N®, Sigma Co.) with a mean value of 9.47U/L yielded a within-run and between-run CVs are 5.6% (N=15) and 6.9% (N=14) respectively. Save in 75 CWP was 20.3±5.7U/L (mean±s.d.); higher than in healthy controls (13.4±3.9U/L, P<0.01). No correlation was found between SACE, sex, and age. The results suggest that the measurement for SACE and follow-up SACE in coal workers may be a useful diagnostic tools for CWP.

MeSH Terms

Anthracosis*
Coal*
Fasting
Follow-Up Studies
Humans
Methods
Coal