Pediatr Gastroenterol Hepatol Nutr.  2017 Mar;20(1):14-21. 10.5223/pghn.2017.20.1.14.

Surgery in Pediatric Crohn's Disease: Indications, Timing and Post-Operative Management

Affiliations
  • 1Department of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, Korea. PEDKS@yuhs.ac

Abstract

Pediatric onset Crohn's disease (CD) tends to have complicated behavior (stricture or penetration) than elderly onset CD at diagnosis. Considering the longer duration of the disease in pediatric patients, the accumulative chance of surgical treatment is higher than in adult onset CD patients. Possible operative indications include perianal CD, intestinal stricture or obstruction, abdominal abscess or fistula, intestinal hemorrhage, neoplastic changes and medically untreatable inflammation. Growth retardation is an operative indication only for pediatric patients. Surgery can affect a patient's clinical course, especially for pediatric CD patient who are growing physically and mentally, so the decision should be made by careful consideration of several factors. The complex and diverse clinical conditions hinder development of a systemized treatment algorithm. Therefore, timing of surgery in pediatric CD patients should be determined with individualized approach by an experienced and well organized multidisciplinary inflammatory bowel disease team. Best long-term outcomes will require proactive post-operative monitoring and therapeutic modifications according to the conditions.

Keyword

Inflammatory bowel diseases; Crohn disease; Colorectal surgery; Child

MeSH Terms

Abdominal Abscess
Adult
Aged
Child
Colorectal Surgery
Constriction, Pathologic
Crohn Disease*
Diagnosis
Hemorrhage
Humans
Inflammation
Inflammatory Bowel Diseases
Intestinal Fistula

Cited by  2 articles

Early Biologic Treatment in Pediatric Crohn's Disease: Catching the Therapeutic Window of Opportunity in Early Disease by Treat-to-Target
Ben Kang, Yon Ho Choe
Pediatr Gastroenterol Hepatol Nutr. 2018;21(1):1-11.    doi: 10.5223/pghn.2018.21.1.1.

Use of Anti-TNF Alpha Blockers Can Reduce Operation Rate and Lead to Growth Gain in Pediatric Crohn's Disease
Min Hyung Woo, Young Hoon Cho, Min Ji Sohn, Eun Joo Lee, Ju Whi Kim, Jin Soo Moon, Jae Sung Ko, Hyun-young Kim
Pediatr Gastroenterol Hepatol Nutr. 2019;22(4):358-368.    doi: 10.5223/pghn.2019.22.4.358.


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