Korean J Gastroenterol.  2015 Mar;65(3):182-185. 10.4166/kjg.2015.65.3.182.

A Case of Pleomorphic Liposarcoma Originating from Mesentery

• Choi JY
• Kim JE
• Lee SM
• Kang HJ
• Sung JH
• Koh BS
• Park JS
• Kim ID
• Baik SY

• KMID: 2373205
• DOI: http://doi.org/10.4166/kjg.2015.65.3.182

Abstract

Liposarcoma is one of the most common soft tissue sarcomas that occurs in adults and is currently divided into five main subgroups: well-differentiated, myxoid, round cell, pleomorphic, and dedifferentiated. Primary mesenteric liposarcoma is extremely rare, and the treatment strategy is surgical resection with a wide free margin, often followed by radiation and adjuvant chemotherapy if distant metastasis is not detected. A 73-year-old male patient presented with lower abdominal distension. Abdominal CT scan revealed a large homogeneously enhancing mass lesion abutting the sigmoid colon and urinary bladder. At laparotomy, the solid mass measured 28x26x12 cm in size, was well-demarcated, and originated from the mesentery of the middle ileum. It was removed along with some small intestine (ileocecal valve upper 50-150 cm) and ileal mesentery because of adhesion. Histologically, the tumor proved to be pleomorphic liposarcoma. The patient did not undergo any adjuvant treatment following surgery, but he remains disease free until 33 months after surgery. Herein, we report a case of pleomorphic liposarcoma arising from small bowel mesentery.

Keyword

Liposarcoma, pleomorphic; Mesentery

MeSH Terms

Aged
Humans
Liposarcoma/*diagnosis/pathology/surgery
Male
Mesentery/*pathology
Peritoneal Neoplasms/*diagnosis/pathology/surgery
Tomography, X-Ray Computed

Figure

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  Fig. 1. (A, B) Pre-operative enhanced computed tomography findings. The peritoneal cavity is almost occupied by heterogeneously enhancing huge mass measuring about 25×10 cm with multiple area of necrosis and inseparable from the sigmoid colon. (C, D) Post-operative enhanced computed tomography taken at 25 month after surgical extirpation. Intra-abdominal structures are normal and there is no evidence of recurrence.

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  Fig. 2. Gross and microscopic findings (H&E, ×100). (A) A yellowish hard solid multinodular mass originating from the small bowel mesentery measures 28×26×12 cm in size (arrows). (B) Tumor shows a thick fibrous capsule.(C) Pleomorphic spindle-shaped cells and multinucleated giant lipoblasts with floret-like features (arrows) are seen.

Reference

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