Korean J Gastroenterol.  2009 Oct;54(4):243-247. 10.4166/kjg.2009.54.4.243.

A Case of Liposarcoma Arising in the Mesentery

• Son BS
• Seok SJ
• Chung SK
• Lee JS
• Lee MS
• Shim CS
• Hur KY
• Jin SY

• KMID: 783230
• DOI: http://doi.org/10.4166/kjg.2009.54.4.243

Abstract

A liposarcoma is the most common soft tissue sarcoma in adults with an incidence of about 20% of all soft tissue sarcomas. Although incidence differs from a region of origination, a case arisen from mesentery has rarely been reported. We experienced a case of liposarcoma arising from the mesentery of a 51-year-old male patient. He was treated by wide excision. Histologically, the tumor was composed of a mixed well-differentiated liposarcoma with myxoid and spindle cell type.

Keyword

Mesentery; Liposarcoma

MeSH Terms

Diagnosis, Differential
Fluorodeoxyglucose F18/diagnostic use
Humans
Liposarcoma/*diagnosis/pathology/surgery
Magnetic Resonance Imaging
Male
Mesentery/*pathology
Middle Aged
Tomography, X-Ray Computed

Figure

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  Fig. 1. CT findings showed a large, heterogeneous, left-sided abdominal mass that did not extend across the midline into the right abdomen. The mass displaced the descending and transverse colon anteriorly and pushed most of the bowel into the right abdomen.

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  Fig. 2. (A) Axial T2-weighted fast spin echo MR image showed a large tumor with heterogeneous high signal intensity and central intermediate signal intensity in left peritoneal cavity. (B) Coronal contrast-enhanced T1-weighted MR image showed heterogenous peripheral enhancement in the mass.

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  Fig. 3. Integrated 18F-PET CT showed a FDG uptake in the peripheral portion of the mass (peak SUV=2.37) with central pho-topenic region.

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  Fig. 4. Cut surfaces of the mesenteric masses. (A) The cut surface of the largest mass exhibited tan brown nodule in grey-yellow solid nodule. (B) The macroscopic findings of smaller masses resembled lipomas.

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  Fig. 5. Microscopic findings of liposarcoma masses. (A) Two smaller masses consisted of many mature adipocytes and intervening few atypical spindle cells. (B) The central nodule of the largest mass demonstrated proliferation of stellate spindle cells and plexiform vasculature on rich myxoid stroma. (C) The peripheral portion of the largest mass contained areas of sclerosing variant with bony metaplasia (A & C: H-E, ×100; B: H-E, ×40).

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