J Gastric Cancer.  2011 Jun;11(2):109-115.

Efficacy of Endoscopic Ultrasonography for Prediction of Tumor Depth in Gastric Cancer

• Park JM
• Ahn CW
• Yi X
• Hur H
• Lee KM
• Cho YK
• Han SU

Abstract

PURPOSE
As the proportion of early gastric cancer (EGC) has recently been increased, minimally invasive treatment is currently accepted as main therapy for EGC. Accurate preoperative staging is very important in determining treatment options. To know the accuracy of endoscopic ultrasonography (EUS), we compared the depth of invasion of the tumor with preoperative EUS and postoperative pathologic findings.
MATERIALS AND METHODS
We retrospectively analyzed 152 patients who underwent EUS before laparoscopic gastrectomy. The preoperative EUS results were compared with the pathological findings.
RESULTS
The overall proportion of coincidence for depth of invasion between EUS and pathologic results was 41.4%. Univariate analysis showed that the rate of corrected prediction of EUS for tumor depth significantly decreased for the lesions more than 3cm in diameter (P=0.033), and those with a depressed morphology (P=0.035). In multivariate analysis, the depressed type (P=0.029, OR=2.873) and upper lesion (P=0.035, OR=2.151) was the significantly independent factors influencing the inaccurate prediction of EUS for tumor depth.
CONCLUSIONS
When we decide the treatment modality considering the clinical depth of invasion by EUS, the possibility of discordance with pathologic results should be considered for the lesions located in the upper third of the stomach and with a depressed morphology.

Keyword

Stomach neoplasms; Endosonography; Neoplasm invasiveness

MeSH Terms

Endosonography
Gastrectomy
Humans
Multivariate Analysis
Neoplasm Invasiveness
Retrospective Studies
Stomach
Stomach Neoplasms

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