Pediatr Gastroenterol Hepatol Nutr.  2016 Sep;19(3):207-209. 10.5223/pghn.2016.19.3.207.

Corrosive Esophagitis with Benzalkonium Chloride in a Two Days Old Neonate

Affiliations
  • 1Department of Pediatric Gastroenterology, Hepatology and Nutrition, Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey. hasretayyildiz@yahoo.com

Abstract

Benzalkonium chloride (BAC) is a caustic agent which is used in farms, homes and hospitals for cleaning skin and wounds as an antiseptic solution. It may lead to digestive system injuries in case of ingestion. We present a two-days-old newborn case which was carried to the emergency unit with complaints of poor breastfeeding, uneasiness and crying for 4-6 hours. Her mom confessed that she had given a spoon of 10% BAC solution for her cough. Initial laboratory tests were in normal ranges. A gastroscopy performed in the second hour of her admission revealed an hyperemic and edematous mucosa in the middle third of esophagus and a circumferential ulceration followed in the distal portion. Hereupon, a conservative treatment for 10 days was administered and the control gastroscopy demonstrated that the damage was almost totally improved. She was the youngest case with this etiology and successfully treated with conservative approach.

Keyword

Benzalkonium chloride; Corrosive esophagitis; Neonate

MeSH Terms

Agriculture
Benzalkonium Compounds*
Breast Feeding
Cough
Crying
Digestive System
Eating
Emergency Service, Hospital
Esophagitis*
Esophagus
Gastroscopy
Humans
Infant, Newborn*
Mucous Membrane
Reference Values
Skin
Ulcer
Wounds and Injuries
Benzalkonium Compounds

Figure

  • Fig. 1 Circumferential mucosal ulceration in the distal third of esophagus two hours after ingestion of benzalkonium chloride.

  • Fig. 2 Recovery of ulcerated distal esophageal mucosa after 10 days of treatment.


Reference

1. Haller JA, Andrews HG, White JJ, Tamer MA, Cleveland WW. Pathophysiology and management of acute corrosive burns of the esophagus: results and treatment in 258 children. J Pediatr Surg. 1971; 6:578–584.
2. Okan F, Coban A, Ince Z, Can G. A rare and preventable cause of respiratory insufficiency ingestion of benzalkonium chloride. Pediatr Emerg Care. 2007; 23:404–406.
3. Kushimo T, Ekanem MM. Acid ingestion in a 2-day old baby. West Afr J Med. 1997; 16:121–123.
4. Turan C, Ozkan U, Ozokutan BH, Ozdemir M, Okur H, Küçükaydin M. Corrosive injuries of the esophagus in newborns. Pediatr Surg Int. 2000; 16:483–484.
Article
5. Altuntaş N, Sarıcı D, Çelebi TA, Kışlal FM, Karadağ F, Özkan B, et al. Benzalkonyum klorür: yenidoğanın nadir bir kimyasal perine yanğı nedeni. Pam med J. 2014; 7:159–162.
6. Hardwicke J, Azad S. Temporary henna tattooing in siblings-an unusual chemical burn. Burns. 2006; 32:1064–1065.
Article
7. Estrera A, Taylor W, Mills LJ, Platt MR. Corrosive burns of esophagus and stomach: a recommendation for an aggressive surgical approach. Ann Thorac Surg. 1986; 41:276–283.
Article
8. Wilson JT, Burr IM. Benzalkonium chloride poisoning in infant twins. Am J Dis Child. 1975; 129:1208–1209.
Article
Full Text Links
  • PGHN
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr