Ann Dermatol.  1993 Jan;5(1):51-55. 10.5021/ad.1993.5.1.51.

A Case of Linear IgA Bullous Dermatosis

• Hwang YJ
• Yang HY
• Lee CW
• Kim JH

• KMID: 2361737
• DOI: http://doi.org/10.5021/ad.1993.5.1.51

Abstract

This paper deals with a case of linear IgA bullous dermatosis (LABD). The patient was a 58-year-old woman who had multiple pruritic vesicles on the trunk, buttocks, thighs, tongue and buccal mucosa. A biopsy of a lesion revealed subepidermal vesicles. Direct immunofluorescence examination of the perilesional skin showed a linear deposition of IgA along the basement membrane zone (BMZ). Indirect immunofluorescence examination, using NaCl split skin as substrate, showed antiBMZ IgA antibodies bound only to the epidermal side. The skin lesions responded well to oral dapsone therapy.

Keyword

Linear IgA bullous dermatosis

MeSH Terms

Antibodies
Basement Membrane
Biopsy
Buttocks
Dapsone
Female
Fluorescent Antibody Technique, Direct
Fluorescent Antibody Technique, Indirect
Humans
Immunoglobulin A
Linear IgA Bullous Dermatosis*
Middle Aged
Mouth Mucosa
Skin
Thigh
Tongue
Antibodies
Dapsone
Immunoglobulin A