J Korean Med Sci.  2015 Dec;30(12):1911-1914. 10.3346/jkms.2015.30.12.1911.

The Use of Extracorporeal Circulation in Suspected Brain Dead Organ Donors with Cardiopulmonary Collapse

• Lee H
• Cho YH
• Sung K
• Yang JH
• Chung CR
• Jeon K
• Suh GY

• KMID: 2359979
• DOI: http://doi.org/10.3346/jkms.2015.30.12.1911

Abstract

Donor shortage is a major limitation in organ transplantation. Several studies have reported that extracorporeal membrane oxygenation (ECMO)-assisted organ donation can be successfully completed without inducing warm ischemia in patients with brain death. The present report described clinical experience of three patients (23-yr old man, 32-yr old man, and 41-yr old woman) who underwent ECMO for the evaluation of brain death and organ donation. They donated six kidneys, three livers, and one both lungs without warm ischemia by ECMO. Six kidney recipients successfully recovered normal status without hemodialysis and two liver recipients survived with normal liver functions, but one liver recipient and one lung recipient died 3 and 15 days after transplantation. Our report strongly encourages ECMO-assisted organ donation from brain death patients with refractory cardiopulmonary collapse to achieve improved organ transplantation.

Keyword

Extracorporeal Membrane Oxygenation; Brain Death; Tissue Organ Procurement

MeSH Terms

Adult
*Brain Death/diagnosis
*Extracorporeal Membrane Oxygenation
Female
Heart Arrest
Humans
Male
Middle Aged
Organ Transplantation
*Tissue Donors
Tissue and Organ Harvesting
Tissue and Organ Procurement/*methods
Treatment Outcome
Young Adult

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