Ann Dermatol.  1998 Jul;10(3):175-178. 10.5021/ad.1998.10.3.175.

A Case of Trichilemmal Carcinoma

Abstract

Trichilemmal carcinoma is a rare tumor that is located predominantly on sun-exposed skin of the elderly. It is thought to be related to the external root sheath of the hair follicle and the malignant counterpart of a trichilemmoma. We report a case of trichilemmal carcinoma in a 88-year-old woman who had a 10 year history of a single, dark brown tumor on the right preauricular region. In her past medical history, it had been excised twice at a private clinic without a histopathological evaluation and recurred 2 years later. Histopathological findings showed atypical clear cells resembling those of the outer root sheath. Tumor cells showed PAS-positive cytoplasm. Immunohistochemistry revealed positive high molecular weight cytokeratin expression. To our knowledge, this is the second case of trichilemmal carcinoma in the Korean literature. (Ann Dermatol 100) 175178, 1998).

Keyword

Trichilemmal carcinoma; High molecular weight cytokeratin

MeSH Terms

Aged
Aged, 80 and over
Cytoplasm
Female
Hair Follicle
Humans
Immunohistochemistry
Keratins
Molecular Weight
Skin
Keratins
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