Korean J Clin Pharm.  2016 Sep;26(3):264-266. 10.0000/kjcp.2016.26.3.264.

Cold Medications Aggravated Rhabdomyolysis Symptoms Induced by Building Construction Work and Strenuous Exercise: a Case Report

Affiliations
  • 1College of Pharmacy, Research Institute of Pharmaceutical Science, Gyeongsang National University, Gyeongnam 52828, Republic of Korea.
  • 2College of Pharmacy, Chosun University, Gwangju 61452, Republic of Korea.
  • 3Division of Nephrology, Department of Internal Medicine, Chonnam National University Hospital and Medical School of Chonnam National University, Gwangju 61469, Republic of Korea. skimw@jnu.ac.kr

Abstract

SUMMARY: A 21-year-old healthy Korean man worked on a building construction site every day for almost 2 months and exercised every day for 1 or 2 hours after working hard. He felt dizziness, nausea, and experienced vomiting and body aches immediately after exercise and immediately took cold medicines including acetaminophen, cimetidine, bepotastine, and Codenal? complex for the common cold symptoms for 2 days because he was scheduled to participate in navy training at that time. He complained of severe trapezius pain and aches in his left calf 3 days after joining the Navy training. Testing revealed creatine phosphokinase (CPK) 6260 U/L, myogloblin 176 mcg/L in the urine, liver enzymes increased, and oliguria, suggesting rhabdomyolysis. He recovered with intravenous fluids without any complications.

Keyword

Rhabdomyolysis; creatine phosphokinase (CPK); myogloblin; building construction work; exercise; cold medicines

MeSH Terms

Acetaminophen
Cimetidine
Common Cold
Creatine Kinase
Dizziness
Humans
Liver
Nausea
Oliguria
Rhabdomyolysis*
Superficial Back Muscles
Vomiting
Young Adult
Acetaminophen
Cimetidine
Creatine Kinase
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