J Korean Ophthalmol Soc.  2016 Aug;57(8):1248-1253. 10.3341/jkos.2016.57.8.1248.

Preferences and Trends in the Treatment of Diabetic Retinopathy in Korea and Japan

• Kim JY
• Shin JP
• Jo YJ
• Park TK
• Yu SY
• Chang WH
• Oh JR
• Lee JE
• Lee JE

• KMID: 2349071
• DOI: http://doi.org/10.3341/jkos.2016.57.8.1248

Abstract

PURPOSE
To evaluate preferences and trends in the management of diabetic retinopathy in Korea and Japan.
METHODS
An Internet survey comprised of 49 questions was sent to the members of Korean Retina Society (KRS) and Japanese Society of Ophthalmic Diabetology (JSOD). The survey was conducted during the period between June 2012 and July 2012.
RESULTS
Ninety-one of 210 members of the KRS (43%) and 120 of 754 members of the JSOD (16%) participated in the survey. For diffuse diabetic macular edema, 'intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) followed by focal laser treatment' was the most preferred treatment in Korea (48%), while 'sub-tenon steroid injection followed by focal laser treatment' was the most common procedure in Japan (33%). Vitrectomy was the second most common procedure in Japan (18%). In contrast, none of the KRS members preferred vitrectomy in this situation. For refractory diabetic macular edema, however, vitrectomy with or without the use of anti-VEGF was chosen in 75% of the KRS members. In Japan, vitrectomy without the use of intravitreal injection of anti-VEGF or steroid was relatively more preferred. Small-gauge (G) vitrectomy using either a 23 G or 25 G needle was popular in both countries (90% in Korea, 64% in Japan).
CONCLUSIONS
Although the trends in diagnostic and surgical environments were similar in Korea and Japan, the preferred treatment approaches for diabetic macular edema were different. Sub-tenon steroid injection and vitrectomy were preferred in Japan, while anti-VEGF injection was most commonly employed in Korea.

Keyword

Diabetic retinopathy; Japan; Korea; Preferences and trends survey

MeSH Terms

Asian Continental Ancestry Group
Diabetic Retinopathy*
Endothelial Growth Factors
Humans
Internet
Intravitreal Injections
Japan*
Korea*
Macular Edema
Needles
Retina
Vitrectomy
Endothelial Growth Factors

Figure

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  Figure 1. What is your primary practice setting (%, total N = 91 and 120 in Korea and Japan, respectively)?

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  Figure 2. How long have you been in practice, after completion of fellowship (%, total N = 91 and 120 in Korea and Japan, respectively)?

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  Figure 3. In addition to your clinical examination, what retinal imaging modality/modalities do you most-commonly use when assessing diabetic macular edema (%, total N = 91 and 120 in Korea and Japan, respectively)? OCT = optical coherence tomography.

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  Figure 4. How would you manage a patient with vision of 20/25 (with no subjective visual complaints), clinically significant diabetic macular edema and clear evidence of intraretinal fluid on spectral domain optical coherence tomography (OCT) (%, total N = 91 and 120 in Korea and Japan, respectively)? anti-VEGF = anti-vascular endothelial growth factor.

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  Figure 5. What combination of therapies do you most commonly use for non-diffuse clinically significant diabetic macular edema (Vision 20/50) (%, total N = 91 and 120 in Korea and Japan, respectively)? anti-VEGF = anti-vascular endothelial growth factor.

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  Figure 6. What combination of therapies do you most commonly use for diffuse diabetic macular edema (Vision 20/50) (%, total N=91 and 120 in Korea and Japan, respectively)? an-ti-VEGF = anti-vascular endothelial growth factor; Avastin®= Bevacizumab (Genentech, South San Francisco, CA, USA).

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  Figure 7. How would you manage a patient with diffuse diabetic macular edema (Vision 20/80) refractory to multiple focal and grid laser treatments, intravitreal anti-VEGF therapy and intravitreal steroid therapy (%, total N=91 and 120 in Korea and Japan, respectively)? anti-VEGF = anti-vascular endothelial growth factor.

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  Figure 8. Which wavelength do you use most often for pan retinal photocoagulation (PRP) treatment (%, total N=91 and 120 in Korea and Japan, respectively)?

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  Figure 9. What is your preferred laser treatment method for diffuse diabetic macular edema (with or without combined intravitreal injection of anti-vascular endothelial growth factor [anti-VEGF]) (%, total N=91 and 120 in Korea and Japan, respectively)? ETDRS = Early Treatment of Diabetic Retinopathy Study.

Reference

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