Clin Endosc.  2016 Jul;49(4):399-401. 10.5946/ce.2015.144.

Successful Endoscopic Ultrasound-Guided Alcohol Ablation of Sporadic Insulinoma Using Three-Dimensional Targeting (with Video)

• Trikudanathan G
• Mallery SJ
• Amateau SK

• KMID: 2348263
• DOI: http://doi.org/10.5946/ce.2015.144

Abstract

Surgical resection is considered the standard of care in the management of symptomatic insulinoma. In this video, we describe the successful management of a symptomatic insulinoma by using linear array endoscopic ultrasound (EUS)-guided ethanol ablation in a poor surgical candidate. EUS-guided ethanol ablation of insulinoma offers a safer, effective, and less invasive alternative to surgery.

Keyword

Insulinoma; Endoscopic ultrasound-guided alcohol ablation

MeSH Terms

Ethanol
Insulinoma*
Standard of Care
Ultrasonography
Ethanol

Figure

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  Fig. 1. (A) Cytologic preparations demonstrate a monomorphous population of neoplastic cells with neuroendocrine features Diff-Quik stain (×20) highlighting typical 3-dimensional clusters. (B) Chromogranin (×100) and (C) synaptophysin immunohistochemical stains both positive for the genetic markers of neuroendocrine differentiation (×40).

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