J Korean Soc Radiol.  2010 Jun;62(6):575-578.

MR Findings of Inflammatory Myofibroblastic Tumor of the Thigh: A Case Report

Affiliations
  • 1Department of Radiology, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea. kangbs0708@freechal.com
  • 2Department of Pathology, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea.
  • 3Department of Orthopaedic Surgery, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea.

Abstract

Inflammatory myofibroblastic tumor is a rare benign condition of an unknown etiology and it may be clinically misdiagnosed as a malignant tumor. We examined a 28-year-old male with a slowly-growing mass in his left thigh. The MR images showed a relatively well-defined, intermuscular mass lesion with heterogeneous enhancement. The histopathologic examination of the resected specimen revealed inflammatory myofibroblastic tumor. We report here on the MR findings of inflammatory myofibroblastic tumor of the thigh in this patient.


MeSH Terms

Adult
Granuloma, Plasma Cell
Humans
Magnetic Resonance Imaging
Male
Myofibroblasts
Thigh

Figure

  • Fig. 1 A 28-year-old male with a 5×5×8 cm mass in the left thigh. A. The axial FSE T1-weighted MR image (TR/TE = 606/20) shows heterogeneously low signal intensity in the mass, and the mass was located in the intermuscular space between the vastus medialis, sartorius, gracilis and adductor muscles. B. The axial FSE fat-saturated T2-weighted MR image (TR/TE = 3510/107) shows heterogeneously low signal intensity with multifocal dark signal intensities in the mass. C, D. The axial and coronal fat-saturated FSE T1-weighted MR images (TR/TE = 967/20) obtained after MR contrast injection show diffusely heterogeneous enhancement with multifocal non-enhanced portions. E. H & E staining shows that mixed inflammatory cells, such as lymphocytes and plasma cells, were infiltrated between the spindle cells (× 200). F. Immunohistochemical staining for anaplastic lymphoma kinase (ALK) shows a positive reaction (× 200).


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