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Case Report of Nodular Fasciitis in the Conjunctiva

Kim JH, Na KS, Park CH, Lee SJ, Oh TH, Kim HS

PURPOSE: We report a case of nodular fasciitis of the conjunctiva that has not been previously reported in the Republic of Korea. CASE SUMMARY: A 18-year-old female patient presented with a...
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Inflammatory Endobronchial Myofibroblastic Tumor: A Case Report

Nam SW, Jeong YJ, Lee G, Lee JW, Eom JS, Cho JS, Park WY, Park SM

Inflammatory myofibroblastic tumor is a rare benign lesion that accounts for 0.04–1% of all lung tumors and usually appears as a solitary pulmonary nodule or mass. Here, we report the...
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Follistatin Mitigates Myofibroblast Differentiation and Collagen Synthesis of Fibroblasts from Scar Tissue around Injured Flexor Tendons

Kang YM, Lee SK, Chun YM, Choi YR, Moon SH, Lee HM, Kang HJ

PURPOSE: The aim of this study was to investigate the effect of FST gene on the inhibition of fibrosis in fibroblastic cells from scar tissue around repaired zone II flexor...
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The Significance of NOTCH Pathway in the Development of Fibrosis in Systemic Sclerosis

Zmorzyński S, Styk W, Filip AA, Krasowska

Systemic sclerosis (SSc) is an autoimmune disorder characterized by the fibrosis of skin, heart, lung, and kidney as well. Excessive activation of fibroblasts is associated with higher expression of Notch1...
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Laryngeal Inflammatory Myofibroblastic Tumor: Case Series and Literature Review

Park KI, Kim SH, Park IS, Kim JW

Inflammatory myofibroblastic tumor (IMT) is a rare benign tumor, that is composed of myofibroblastic spindle cells with inflammatory cells. IMTs usually occur in lungs, intestine organs, orbits and paranasal sinuses,...
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Effect of Manuka Honey on Transforming Growth Factor Beta-1-Induced Extracelluar Matrix Production in Nasal Polyp Derived Fibroblasts

Kil BK, Kim BM, Kang BJ, Ye MK, Shin SH

BACKGROUND AND OBJECTIVES: Manuka honey has anti-microbial, anti-inflammatory, and anti-proliferative action with a high concentration of methylglyoxal compound. It is also effective in killing Staphylococcus aureus biofilm and effective for...
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A Case of Solitary Fibrous Tumor of Hard Palate

Shin SH, Hong MP, Cha YJ, Lim JY

Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm first described and often encountered in the pleura. It has also been documented in a variety of extrapleural sites including the...
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A Case of Cutaneous Inflammatory Myofibroblastic Tumor

Kim Y, Lee HJ, Shin K, Kim WI, Lee WK, Kim HS, Ko HC, Kim BS, Kim MB, Yang MY

  • KMID: 2470224
  • Korean J Dermatol.
  • 2019 Dec;57(10):642-644.
No abstract available.
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Metformin-loaded Citric Acid Cross-linked Agarose Films in the Prevention of Postoperative Abdominal Adhesion

Moon JH, Park JH, Jeong JH, Sung NS, Jeong YG, Song KC, Ahn JP, Lee NS, Han SY

Postoperative abdominal adhesion (PAA) causes significant long-term postoperative morbidity. Although numerous physical anti-adhesion barriers (AAB) are used as therapeutical interventions, none of them has achieved sustained success. As a potential...
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Selective Inhibition of β-Catenin/Co-Activator Cyclic AMP Response Element-Binding Protein-Dependent Signaling Prevents the Emergence of Hapten-Induced Atopic Dermatitis-Like Dermatitis

Matsuda-Hirose H, Yamate T, Goto M, Katoh A, Kouji H, Yamamoto Y, Sakai T, Uemura N, Kobayashi , Hatano Y

BACKGROUND: The canonical Wnt/β-catenin signaling pathway is a fundamental regulatory system involved in various biological events. ICG-001 selectively blocks the interaction of β-catenin with its transcriptional co-activator cyclic AMP response...
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A Case of Laryngeal Inflammatory Myofibroblastic Tumor

Park SG, Kim Y, Woong JH, Song CM

Inflammatory myofibrolastic tumor (IMT) is a rare borderline neoplasm. It frequently occurs in the lung but occasionally occurs in extrapulmonary sites such as the genitourinary tract, gastrointestinal tract, breast, salivary...
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CT and MRI Features of Solitary Fibrous Tumor of the Liver: A Case Report

Nah YK, Shin SS, Heo SH, Jeong YY

Solitary fibrous tumors (SFTs) are a unique group of soft tissue tumors originating from fibroblastic or myofibroblastic tissue. SFTs rarely occur in the liver, with less than 30 cases reported...
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Inflammatory Myofibroblastic Tumor of the Retroperitoneum Including Chronic Granulomatous Inflammation Suggesting Tuberculosis: A Case Report

Kim Y, Park JW, Kim S, Lee KY, Bae J, Jeon YK, Im JM, Ryoo SB, Jeong SY, Park KJ

An inflammatory myofibroblastic tumor (IMT) is a solid tumor of unknown etiology frequently affecting children and young adults and commonly affecting the lung or orbital region. We present a case...
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Proliferative Myositis on the Tongue

Park MJ, Seong GH, Park M, Choi MS, Hong SP, Park BC, Kim M

  • KMID: 2433641
  • Korean J Dermatol.
  • 2019 Jan;57(1):28-31.
Proliferative myositis is a rare, benign, probably pseudosarcomatous fibroblastic proliferation that typically presents as a rapidly growing soft tissue mass. Its relative rarity, fast growth rate, and unique histopathologic findings...
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An Immunohistochemical and Polarizing Microscopic Study of the Tumor Microenvironment in Varying Grades of Oral Squamous Cell Carcinoma

Khalid A, Siddiqui S, Bordoloi B, Faizi N, Samadi F, Saeed N

BACKGROUND: Invasion of epithelial cells into the connective tissue brings about massive morphological and architectural changes in the underlying stroma. Myofibroblasts reorganize the stroma to facilitate the movement of tumor...
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Case of an Inflammatory Myofibroblastic Tumor of the Duodenum

Park SG, Kim GH, Park HJ, Kahng DH, Lee BE, Park DY

An inflammatory myofibroblastic tumor (IMT) is a rare disease that can occur in a variety of locations, including the lung, orbit, parotid, pleura, and stomach. Despite multiple reports in various...
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Silencing Histone Deacetylase 7 Alleviates Transforming Growth Factor-β1-Induced Profibrotic Responses in Fibroblasts Derived from Peyronie's Plaque

Kang DH, Yin GN, Choi MJ, Song KM, Ghatak K, Minh NN, Kwon MH, Seong DH, Ryu JK, Suh JK

PURPOSE: Epigenetic modifications, such as histone acetylation/deacetylation and DNA methylation, play a crucial role in the pathogenesis of inflammatory disorders and fibrotic diseases. The aim of this study was to...
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Epigenetic Regulation of Nasal Polyp Formation

Park IH, Lee HM

Nasal polyposis is a multi-factorial disease associated with chronic inflammation of the paranasal sinuses. Myofibroblast differentiation and extracellular matrix (ECM) accumulation are involved in the pathogenesis of nasal polyposis. Epigenetics,...
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A Case of Dermatomyofibroma on Inguinal Area in a Middle Aged Woman

Song SE, Hong SG, Jo SY, Heo EP, Ro KW

  • KMID: 2437060
  • Korean J Dermatol.
  • 2018 Dec;56(10):640-641.
No abstract available.
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Clinicopathological Characteristics of Urinary Bladder Tumors in Korean Patients 20 Years or Younger

Kim SC, Park S, Song SH, Kim KS, Park S

BACKGROUND: To investigate the clinicopathological characteristics of urinary bladder tumors, a rare malignancy, in patients 20 years or younger. METHODS: Using a retrospective chart review among patients who received bladder surgery...
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