Psychiatry Investig.  2016 Jul;13(4):468-471. 10.4306/pi.2016.13.4.468.

Treatment-Resistant Depression Entering Remission Following a Seizure during the Course of Repetitive Transcranial Magnetic Stimulation

Affiliations
  • 1Department of Psychiatry, Chonnam National University Medical School, Gwangju, Republic of Korea. jmkim@chonnam.ac.kr

Abstract

Major depressive disorder is often resistant to antidepressant treatment. Repetitive transcranial magnetic stimulation (rTMS) has been used in treatment-resistant depression (TRD). Known adverse events of rTMS include transient headache, local pain, syncope, seizure induction, and hypomania induction. This report outlines a patient with TRD who unexpectedly improved following a seizure during the course of rTMS, which has never been reported.

Keyword

Treatment resistant depression; Transcranial magnetic stimulation; Adverse event; Seizure; Remission

MeSH Terms

Depression*
Depressive Disorder, Major
Depressive Disorder, Treatment-Resistant
Headache
Humans
Seizures*
Syncope
Transcranial Magnetic Stimulation*
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