J Korean Ophthalmol Soc.  2014 Jul;55(7):1007-1016.

Clinical Usefulness of UBM in the Sitting Position in Anterior Chamber Depth and Angle Measurements

• Kim TG
• Moon SW
• Yang JH
• Jin KH

Abstract

PURPOSE
We compared the measurements of anterior chamber depth (ACD) and anterior chamber angle (ACA) using ultrasound biomicroscopy (UBM) in the sitting position compared with IOL Master(R), Pentacam(R), and Spectralis optical coherence tomography (OCT) to evaluate the clinical usefulness of UBM in the sitting position.
METHODS
We evaluated 92 eyes in 47 healthy adults. ACD was measured by IOL Master(R), Pentacam(R), and UBM. ACA was measured using Pentacam(R), UBM, and Spectralis OCT. UBM was performed in the sitting position using bag/balloon technology. Measured values were compared statistically.
RESULTS
ACD measured by IOL Master(R), Pentacam(R), and UBM was 3.57 +/- 0.32 microm, 3.64 +/- 0.33 microm and 3.51 +/- 0.32 microm, respectively. UBM measurements of ACD were significantly shallower than with the other methods (p < 0.001). The results among the 3 methods were strongly correlated (r > 0.8, p < 0.05 in all groups). Mean ACA of 4 directions was not significantly different among the 3 methods (p > 0.05). There was strong correlation between UBM and Spectralis OCT (r = 0.957) but moderate correlation between Pentacam(R) and UBM and Pentacam(R) and Spectralis OCT (r = 0.557, 0.571, respectively, p < 0.05). Specifically, ACA of the superior quadrant showed a low correlation between Pentacam(R) and UBM and Pentacam(R) and Spectralis OCT (r = 0.257, 0.295, respectively).
CONCLUSIONS
ACD measured by UBM in the sitting position was shallower compared to the other methods; however, ACD measured by IOL Master(R), Pentacam(R), and UBM showed significant correlations among the methods. The mean ACA measured by Pentacam(R), UBM, and Spectralis OCT showed no significant differences. Due to the high correlation of ACA measurements between UBM and Spectralis OCT in the present study, UBM is expected to be a good tool for measuring anterior segment parameters.

Keyword

Anterior chamber angle; Anterior chamber depth; Sitting position; UBM

MeSH Terms

Adult
Anterior Chamber*
Humans
Microscopy, Acoustic
Tomography, Optical Coherence

Figure

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  Figure 1. An example of the result of anterior chamber angle (ACA) measurement by Pentacam®. (A) Nasal and temporal angle. (B) Superior and inferior angle. ACA is calculated by integrated software of Pentacam®.

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  Figure 2. ClearScan bag/balloon technology.

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  Figure 3. Ultrasound biomicroscopic image of anterior chamber and lens. Anterior chamber depth 1 (ACD1) is defined as distance from the central corneal epithelium to the anterior surface of lens capsule and ACD2 is defined as distance from the central corneal endothelium to the anterior surface of lens capsule.

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  Figure 4. Ultrasound biomicroscopic (A) and spectralis optical coherence tomography (OCT), (B) image of anterior chamber angle. Anterior chamber angle (ACA) is measured by trabecular iris angle (TIA). TIA is defined as the angle between the iris and trabecular meshwork, with the apex of the angle lying in the angle recess and arms lying at a point 500 μm away from the scleral spur.

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  Figure 5. Bland-Altman plots showing differences in anterior chamber depth (ACD) between devices. The upper and lower dashed lines indicate 95 % limits of agreement and the solid line indicates the mean. UBM = ultrasound biomicroscopy.

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  Figure 6. The correlation plot of the anterior chamber depth (ACD) measured by IOL master®, Pentacam® and ultrasound biomicroscopy (UBM).

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  Figure 7. Bland-Altman plots showing differences in anterior chamber angle (ACA) between devices. The upper and lower dashed lines indicate 95 % limits of agreement and the solid line indicates the mean. OCT = optical coherence tomography; UBM = ultrasound biomicroscopy.

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  Figure 8. The correlation plot of the mean anterior chamber angle (ACA) measured by Pentacam®, Spectralis OCT and ultrasound biomicroscopy (UBM). OCT = optical coherence tomography.

Reference

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