J Korean Ophthalmol Soc.  2009 Dec;50(12):1847-1852. 10.3341/jkos.2009.50.12.1847.

Comparison of Measurement of Anterior Segment Parameters Between Scheimpflug Camera and Ultrasound Biomicroscopy

• Park YS
• Ahn H
• Kim NR
• Ma KT
• Hong S
• Seong GJ
• Kim CY

• KMID: 2212997
• DOI: http://doi.org/10.3341/jkos.2009.50.12.1847

Abstract

PURPOSE
To evaluate the clinical reliability of Pentacam(R) by comparing anterior chamber parameters measured by Oculus Pentacam system (Oculus Inc., Germany) and Hi-scan ultrasound biomicroscopy (OPTIKON 2000, Rome, Italy) in primary angle closure (PAC) and normal patients.
METHODS
A prospective study was performed from June 2006 to January 2007. Fifty-one eyes in 26 primary angle-closure patients and 39 eyes in 20 normal control patients, for a total of 90 eyes of 46 patients were recruited from glaucoma out-patient clinics. The correlation and agreement of both measurements of anterior chamber depth and anterior chamber angle measured by UBM and Pentacam(R) were calculated. Sensitivity and specificity of each tool were also compared and the diagnostic value of angle closure was examined.
RESULTS
Anterior chamber depth measured by UBM and Pentacam(R) showed strong correlation in the normal control group (r=0.821) and PAC group (r=0.957). Anterior chamber angle showed moderate correlation in the normal control group (r=0.523) and PAC group (r=0.456) while good agreement was also observed. In diagnosing angle closure, anterior chamber measurements appear similar in UBM and Pentacam(R) using the ROC curve (AUC of UBM, 0.942; AUC of Pentacam(R), 0.931).
CONCLUSIONS
Pentacam(R) shows high to moderate correlation of anterior chamber measurements and good agreement compared with UBM. Pentacam(R) shows similar ability in diagnosing angle closure compared with UBM and thus is expected to be a good tool in diagnosing angle closure.

Keyword

Anterior chamber angle; Anterior chamber depth; Pentacam; Primary angle-closure glaucoma (PACG); Ultrasound biomicroscope (UBM)

MeSH Terms

Anterior Chamber
Area Under Curve
Eye
Glaucoma
Humans
Microscopy, Acoustic
Outpatients
Prospective Studies
ROC Curve
Rome
Sensitivity and Specificity

Figure

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  Figure 1. Trabeculariris angle (TIA) depicted on an ultrasound biomicroscopic (UBM) image of a normal eye.

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  Figure 2. Bland-Altmann plots of anterior biometry measurements between ultrasound biomicroscopy (UBM) and Pentacam®. Solid line: 95% confidence interval of the difference between the methods.

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  Figure 3. Comparison of ultrasound biomicroscopy (UBM) and Pentacam® measurements of the anterior chamber angle for the diagnosis of primary angle-closure or primary angle-closure glaucoma.

Reference

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