J Korean Ophthalmol Soc.  2013 Sep;54(9):1321-1326.

Clinical Usefulness of a Thermal-Massaging System for Treatment of Dry Eye with Meibomian Gland Dysfunction

Affiliations
  • 1Department of Ophthalmology, Kim's Eye Hospital, Konyang University College of Medicine, Myung-Gok Eye Research Institute, Seoul, Korea. jlchung@kimeye.com

Abstract

PURPOSE
To evaluate the clinical usefulness of KCL 990(R) for the treatment of dry eye with meibomian gland dysfunction (MGD).
METHODS
Patients (n = 54 eyes, 27 subjects) diagnosed with dry eye with MGD were recruited for a prospective, one-month clinical trial. Patients received a twice-a-day 15-minute treatment using the KCL 990(R). Effectiveness parameters included patient symptom scores using the Ocular Surface Disease Index (OSDI) questionnaires, tear osmolarity measured with TearLab(R) (TearLab Corporation, San Diego, CA, USA), classical tear break-up time (TBUT), and objective TBUT value using an Optical Quality Analysis System (OQAS(R), Visiometrics, Castelldefels, Spain). Data are presented for pre-treatment (baseline) and at 1 week and 1 month post-treatment. An objective TBUT value was estimated in each eye when the optical scattering index (OSI) started to increase consistently, and data were obtained at pretreatment (baseline) and at 1 month post-treatment.
RESULTS
The symptom scores on OSDI questionnaires, tear osmolarity, and tear break-up time improved significantly from baseline to one week (p < 0.05). This improvement was maintained with no significant regression at 1 month (p < 0.05). The objective TBUT value decreased significantly at 1 month (p < 0.05).
CONCLUSIONS
KCL 990(R) contributed to improve not only signs and symptoms of dry eye with MGD, but also the function of the tear film and ocular surface.

Keyword

Dry Eye Syndrome; KCL 990(R); Meibomian Gland Dysfunction; Hot compress

MeSH Terms

Dry Eye Syndromes
Eye
Humans
Meibomian Glands
Osmolar Concentration
Prospective Studies
Surveys and Questionnaires
Tears

Figure

  • Figure 1. The objective TBUT parameter is defined as the time that the optical scattering index (OSI) starts to increase con-sistently (black arrow).

  • Figure 2. Photograph of the KCL 990® device.

  • Figure 3. The mean Ocular Surface Disease Index (OSDI) at baseline, 1 week, and at 1 month (* p < 0.05).

  • Figure 4. The mean tear osmolarity at baseline, 1 week, and at 1 month (* p < 0.05).

  • Figure 5. The mean clinical tear break-up time (TBUT) at baseline, 1 week, and at 1 month (* p < 0.05).

  • Figure 6. The mean objective tear break-up time (TBUT) at baseline and at 1 month (* p < 0.05).


Reference

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