J Korean Ophthalmol Soc.  2012 Apr;53(4):588-591.

A Case of Subconjunctival Foreign Body Migration after Collagen-Containing Filler Injection

• Koo NK
• Kim YC
• Kim KS

Abstract

PURPOSE
To report a case of subconjunctival foreign body migration in both eyes after collagen-containing filler injection.
CASE SUMMARY
A 51-year-old female, who had been treated with collagen-containing filler in her eyelid, nose, and forehead for cosmetic complaints four months earlier, presented to our clinic with decreased visual acuity and foreign body sensation in both eyes. Slit lamp examination revealed moderate nucleosclerosis and subcapsular opacity in her crystalline lens, in addition to scattered subconjunctival foreign body infiltration in both eyes. Cataract extraction with posterior chamber lens implantation was performed, and the subconjunctival foreign body was also partially removed. Biopsy of the remaining foreign body was performed, and examination revealed foreign material and multivacuolated cells in the conjunctiva.
CONCLUSIONS
Clinicians and patients should be aware of the risk of migration of collagen-containing filler inject at or near the eyelid, to the eyeball, including the conjunctiva.

Keyword

Collagen; Conjunctiva; Migration

MeSH Terms

Biopsy
Cataract Extraction
Collagen
Conjunctiva
Cosmetics
Eye
Eyelids
Female
Forehead
Foreign Bodies
Foreign-Body Migration
Humans
Lens, Crystalline
Middle Aged
Nose
Sensation
Visual Acuity
Collagen
Cosmetics

Figure

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  Figure 1 Subconjunctival infiltration of collagen implant after collagen-containing filler injection on both eyelid.

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  Figure 2 Removed 2 × 1 mm sized subconjunctival foreign body.

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  Figure 3 Histologic findings of the conjunctiva. (A, B) Microscopic findings revealed multiple multivacuolated cell (arrow) due to foreign body reaction (H&E stain, ×40, ×400).

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