J Korean Ophthalmol Soc.  2007 Dec;48(12):1607-1613.

Clinical Results of Corneal Triple Procedure and Risk Factors for Graft Failure

• Jeong TS
• Moon HJ
• You IC
• Yoon KC

Abstract

PURPOSE: To evaluate the clinical results of corneal triple procedure, as well as the causes and the risk factors for graft failure.
METHODS
Indications, survival period of graft, causes of graft failure, and risk factors for failure in 29 patients (29 eyes) who had undergone penetrating keratoplasty combined with cataract surgery and intraocular lens (IOL) implantation were retrospectively analyzed.
RESULTS
The most common primary indication of corneal triple procedure was bacterial keratitis (24%), followed by corneal trauma, herpes simplex keratitis, and graft failure. The average survival period of corneal graft in corneal triple procedure was 29.2+/-23.2 months. The most common cause of graft failure was allograft rejection (56.3%). The risk factors of graft failure by an univariate analysis were preoperative unfavorable diagnosis (bullous keratopathy, corneal ulcer, and trauma), corneal neovasculization, intraoperative additional procedure (anterior vitrectomy, synechiolysis, and anterior chamber irrigation), immune rejection, and postoperative glaucoma, but were unrelated to methods of cataract surgery, graft size, or IOL position. In a multivariate analysis, graft rejection and corneal neovascularization were identified as risk factors for graft failure in patients undergoing triple procedure.
CONCLUSIONS
Corneal graft in corneal triple procedure had various success rates according to the many factors. Risk factors for graft failure included graft rejection and corneal neovascularization.

Keyword

Corneal triple procedure; Graft failure; Risk factor

MeSH Terms

Allografts
Anterior Chamber
Cataract
Corneal Neovascularization
Corneal Ulcer
Diagnosis
Glaucoma
Graft Rejection
Humans
Keratitis
Keratitis, Herpetic
Keratoplasty, Penetrating
Lenses, Intraocular
Multivariate Analysis
Retrospective Studies
Risk Factors*
Transplants*
Vitrectomy

Figure

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  Figure 1. The distribution of preoperative diagnosis in corneal triple procedure.

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  Figure 2. Kaplan-Meier cumulative survival proportional curve of corneal grafts in corneal triple procedure.

Reference

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