J Korean Ophthalmol Soc.  2006 Oct;47(10):1678-1685.

High Intraocular Pressure-induced Delayed Diffuse Lamellar Keratitis after Laser In Situ Keratomileusis (LASIK)

Affiliations
  • 1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Kerea. kmk9@snu.ac.kr
  • 2Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Korea.
  • 3Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Korea.

Abstract

PURPOSE: To report a case of post-laser in situ keratomileusis (LASIK) delayed diffuse lamellar keratitis (DLK) associated with elevated intraocular pressure (IOP).
METHODS
A retrospective review of the medical record for an eye with delayed-onset DLK.
RESULTS
In an eye treated with topical steroid eye drops after LASIK, DLK suddenly developed at 6 weeks postoperatively. No corneal epithelial defect was found, but IOP was observed to be high. Keratitis regressed as the IOP was controlled with topical antiglaucoma medications. However, DLK recurred at 3 months postoperatively with increasing IOP again caused by continued topical steroid application. Flap irrigation was performed. No microorganism was found on the interface. After discontinuation of topical steroid, IOP was lowered and DLK disappeared completely.
CONCLUSIONS
Elevated IOP can be a causative factor of late-onset DLK after LASIK.

Keyword

DLK; IOP; LASIK; Topical steroid

MeSH Terms

Intraocular Pressure
Keratitis*
Keratomileusis, Laser In Situ*
Medical Records
Ophthalmic Solutions
Retrospective Studies
Ophthalmic Solutions
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