J Korean Ophthalmol Soc.  2004 Nov;45(11):1858-1864.

Quantitative Analysis of Diabetic Macular Edema by Optical Coherence Tomography

• Lee BH
• Cho YW

Abstract

PURPOSE
We measured the foveal thickness (FT) and macular center thickness (MCT) in healthy eyes and diabetic eyes to quantify the macular edema in diabetic eyes with Optical Coherence Tomography (OCT). METHODS: FT and MCT were measured with OCT in 30 healthy eyes, 30 diabetic eyes without macular edema and 30 diabetics eyes with macular edema on slit lamp biomicroscopy. The correlation between FT and MCT and visual acuity was calculated. The sensitivity and specificity of slit lamp biomicroscopy were calculated in comparison with FT and MCT by OCT. RESULTS: In healthy eyes, mean FT was 189 +/- 14 micrometer, and mean MCT was 157 +/- 15 micrometer. The FT and MCT by OCT were found to be linearly correlated with visual acuity in a log minimum angle of resolution (logMAR) scale (P<0.01). The sensitivity and specificity of slit lamp biomicroscopy was 72%, and 90%, respectively, in comparison with FT measured by OCT. The sensitivity and specificity of slit lamp biomicroscopy was 67%, and 100%, respectively, in comparison with MCT measured by OCT. CONCLUSIONS: We were able to quantify diabetic macular edema using OCT. It seems useful to determine the diagnostic criteria of diabetic macular edema with OCT for detecting early macular edema.

Keyword

Diabetic macular edema; Foveal thickness; Macular center thickness; OCT

MeSH Terms

Macular Edema*
Sensitivity and Specificity
Tomography, Optical Coherence*
Visual Acuity