J Korean Pain Soc.  2001 Dec;14(2):171-175.

Comparison of Differential Analgesic and Adverse Effects of 0.125% and 0.15% Ropivacaine Coadministrated Epidurally with Fentanyl

• Yang HJ
• Lee SW

Abstract

BACKGROUND: This purpose of this study is to compare the analgesic efficacy, occurrence of motor block and other side effects of 48 hr continuous postope rative epidural infusions with 0.125% ropivacaine with fentanyl or 0.15% ropivacaine with fentanyl.
METHODS
Forty patients undergoing Cesarean section were randomly allocated into two groups. Both groups received epidural injection of 2.0% lidocaine 19 ml and 0.75% ropivacaine 2 5 ml with fentanyl 50ng for 20 minutes before surgery. Following surgery, a continuous epidural infusion using a two-day infusor was given for 40 minutes for post-operative pain control. Group 1 (n = 20) then received 0.125% ropivacaine and 6 ug/ml of fentanyl at a rate of 2 ml/h. Group 2 (n = 20) received 0.15% ropivacaine and 6 ug/ml of fentanyl at the same rate. Visual analog scales (VAS) for pain during rest and movement, sensory change and motor blockade were assessed for 48 hr after surgery.
RESULTS
There were no significant differences in VAS for pain during rest or movement. The incidence of side effects was similar in both groups.
CONCLUSIONS
Using 0.125% ropivacaine with fentanyl via an epidural route provided similar pain relief and side effects as 0.15% ropivacaine with fentanyl.

Keyword

Analgesia; Anesthetics; Epidural; Pain; Postoperative; Ropivacaine

MeSH Terms

Analgesia
Anesthetics
Cesarean Section
Female
Fentanyl*
Humans
Incidence
Infusion Pumps
Injections, Epidural
Lidocaine
Pregnancy
Visual Analog Scale
Anesthetics
Fentanyl
Lidocaine