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A meta-analysis on advantages of peripheral nerve block post-total knee arthroplasty

You D, Qin L, Li K, Li D, Zhao G, Li L

Background: Postoperative pain management is crucial for patients undergoing total knee arthroplasty (TKA). There have been many recent clinical trials on post-TKA peripheral nerve block; however, they have reported inconsistent...
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The Effect of Patient-controlled Intravenous Analgesia (PCIA) on Postoperative Delirium in Patients with Liver Transplantation: a Propensity Score Matching Analysis

Son HJ, Jeong U, Choi K, Park JY, Choi EJ, Ri HS, Lee TB, Choi BH, Choi YJ

Objectives: Postoperative opioid use and pain are related to postoperative delirium. This study aims to compare the incidence of delirium in patients with and without patient-controlled intravenous analgesia (PCIA) among...
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Influence of Epidural Ropivacaine with or without Dexmedetomidine on Postoperative Analgesia and Patient Satisfaction after Thoraco-Lumbar Spine Instrumentation: A Randomized, Comparative, and Double-Blind Study

Qureshi F, Meena SC, Kumar V, Jain K, Chauhan R, Luthra A

Study Design This was a prospective, randomized, and double-blind study. Purpose Thoraco-lumbar spine surgery is associated with severe postoperative pain and can cause chronic pain. We aimed to compare the impact of epidural...
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Comparison between two different concentrations of a fixed dose of ropivacaine in interscalene brachial plexus block for pain management after arthroscopic shoulder surgery: a randomized clinical trial

Lee SC, Jeong JH, Jeong SY, Kim SW, Chung CJ, Choi SR, Kim JH, Park SY

Background: Only a few studies have evaluated the differences between varying concentrations of a fixed dose of local anesthetics. This study was conducted to compare the effects of two different...
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Intravenous patient-controlled analgesia hydromorphone combined with pregabalin for the treatment of postherpetic neuralgia: a multicenter, randomized controlled study

Huang Y, Xu C, Zeng T, Li Z, Xia Y, Tao G, Zhu T, Lu L, Li J, Huang T, Huai H, Ning B, Ma C, Wang X, Chang Y, Mao P, Lin J

Background: Postherpetic neuralgia (PHN) is the most common complication of acute herpes zoster. The treatment of PHN remains a challenge for clinical pain management. Despite the effectiveness of anticonvulsants, antidepressants,...
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Comparison of ultrasonography guided serratus anterior plane block and thoracic paravertebral block in video-assisted thoracoscopic surgery: a prospective randomized double-blind study

Baytar MS, Yılmaz C, Karasu D, Baytar

Background: Various truncal block techniques with ultrasonography (USG) are becoming widespread to reduce postoperative pain and opioid requirements in video-assisted thoracoscopic surgery (VATS). The primary aim of our study was...
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Ultrasound-guided transversalis fascia plane block versus transmuscular quadratus lumborum block for post-operative analgesia in inguinal hernia repair

Fouad AZ, Abdel-Aal IRM, Ali Gadelrab MRM, Mohammed HMEHS

Background: Inguinal hernia repair is one of the most commonly performed surgical procedures. Regional blocks might provide excellent analgesia and reduce complications in the postoperative period. We aimed to compare...
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Continuous wound infiltration of ropivacaine for reducing of postoperative pain after anterior lumbar fusion surgery: a clinical retrospective comparative study

Lee SM, Yun DJ, Lee SH, Lee HC, Joeng KH

Background: Local anesthetic infiltration at the site of a surgical wound is commonly used to control postoperative pain. In this study, we examined the effectiveness of continuous local infiltration at...
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Prevention of epidural catheter migration: a comparative evaluation of two tunneling techniques

Gautam S, Agarwal A, Das PK, Khuba S, Kumar S

Background Epidural analgesia failure episodes can be reduced by catheter fixation techniques with a lower incidence of catheter migration. In this clinical study, we compared the roles of two epidural catheter...
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Bee venom reduces burn-induced pain via the suppression of peripheral and central substance P expression in mice

Kang DW, Choi JG, Kim J, Park JB, Lee JH, Kim HW

Background: Scalding burn injuries can occur in everyday life but occur more frequently in young children. Therefore, it is important to develop more effective burn treatments. Objectives: This study examined the...
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The efficacy of ultrasound-guided erector spinae plane block after mastectomy and immediate breast reconstruction with a tissue expander: a randomized clinical trial

Park S, Park J, Choi JW, Bang YJ, Oh EJ, Park J, Hong KY, Sim WS

Background: We aimed to investigate the analgesic efficacy of an erector spinae plane block (ESPB) in immediate breast reconstruction (IBR) with a tissue expander. Methods: Adult women undergoing IBR with a...
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Systemically administered neurotensin receptor agonist produces antinociception through activation of spinally projecting serotonergic neurons in the rostral ventromedial medulla

Li Y, Kang DH, Kim WM, Lee HG, Kim SH, You HE, Choi JI, Yoon MH

Background: Supraspinal delivery of neurotensin (NTS), which may contribute to the effect of a systemically administered agonist, has been reported to be either pronociceptive or antinociceptive. Here, we evaluated the...
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Mirogabalin: could it be the next generation gabapentin or pregabalin?

Kim JY, Abdi S, Huh B, Kim KH

Except for carbamazepine for trigeminal neuralgia, gabapentinoid anticonvulsants have been the standard for the treatment of neuropathic pain. Pregabalin, which followed gabapentin, was developed with the benefit of rapid peak...
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Anesthetic efficacy and safety of 2% lidocaine hydrochloride with 1:100,000 adrenaline and 4% articaine hydrochloride with 1:100,000 adrenaline as a single buccal injection in the extraction of maxillary premolars for orthodontic purposes

Deshpande N, Jadhav A, Bhola N, Gupta M

Background: Palatal injection of local anesthetics is the most painful injection. To obviate the need for palatal injections, local anesthetic agents with diffusibility are being investigated. Hence the present study...
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Analgesic effects and distribution of cutaneous sensory blockade of quadratus lumborum block type 2 and posterior transversus abdominis plane block: an observational comparative study

Aoyama Y, Sakura S, Abe S, Wada M, Saito Y

Background: The posterior transversus abdominis plane block (TAPB) and quadratus lumborum block (QLB) were developed for postoperative pain control after lower abdominal surgery. However, there is little data regarding their...
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Factors Influencing Satisfaction with Patient-Controlled Analgesia Among Postoperative Patients Using a Generalized Ordinal Logistic Regression Model

Baek W, Jang Y, Park CG, Moon M

Purpose: The purpose of this study was to identify the factors affecting the satisfaction with patientcontrolled analgesia (PCA) of patients using a generalized ordinal logistic regression model and to evaluate...
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Role of dexmedetomidine as adjuvant in postoperative sciatic popliteal and adductor canal analgesia in trauma patients: a randomized controlled trial

Ahuja V, Thapa D, Chander A, Gombar S, Gupta R, Gupta S

Background: The effect of dexmedetomidine as an adjuvant in the adductor canal block (ACB) and sciatic popliteal block (SPB) on the postoperative tramadol-sparing effect following spinal anesthesia has not been...
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Analgesic effect of ropivacaine with fentanyl in comparison with ropivacaine alone for continuous femoral nerve block after knee replacement arthroplasty: a prospective, randomized, double-blinded study

Kim GH, Lee JW, Kim GE, Lee SS, Son SL, Kim BU, Cho HN, Kwon MY, Koo MS, Kim JE, Yun MJ

Background: The analgesic effect of perineural opioid in clinical practice are still controversial. This randomized controlled trial compared analgesic effect of ropivacaine with fentanyl or ropivacaine alone for continuous...
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Ultrasound-guided percutaneous intercostal cryoanalgesia for multiple weeks of analgesia following mastectomy: a case series

Gabriel RA, Finneran J, Swisher MW, Said ET, Sztain JF, Khatibi B, Wallace AM, Hosseini A, Trescot AM, Ilfeld BM

Background: Acute post-mastectomy pain is frequently challenging to adequately treat with local anesthetic-based regional anesthesia techniques due to its relatively long duration measured in multiple weeks. Case: We report...
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Continuous quadratus lumborum block as part of multimodal analgesia after total hip arthroplasty: a case report

Bak H, Bang S, Yoo S, Kim S, Lee SY

Background Commonly used epidural or systemic analgesics for pain control after hip surgery carry risk for potential adverse effects. In contrast, the quadratus lumborum block (QLB) utilizes a simple and...
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