J Korean Pediatr Soc.
1997 Feb;40(2):279-283.
A Case of Juvenile Granulosa Cell Tumor of the Ovary
- Affiliations
-
- 1Department of Pediatrics, Presbyterian Medical Center, Chonju, Korea.
- 2Department of Pathology, Presbyterian Medical Center, Chonju, Korea.
Abstract
- Juvenile granulosa cell tumor (JGCT) is one of the sex cord stromal tumors of the ovary ocurring in the first two decades of life. These tumors are different from adult granulosa cell tumor (AJCT) with regard to clinical and pathological fetures. Follicles are often irregular, Call-exner bodies are rare, and luteinization is frequent. The tumor may be solid, cystic, or both. The most common presenting symptoms are abnormal uterine bleeding and pain. Breast swelling, pain and tenderness may also be associated with unopposed estrogen secretion by granulosa cell tumors. The tumor should be removed as soon as the diagnosis is estabilished. The juvenile granulosa cell tumor has a good overall prognosis because fewer than 5% of these tumors in children are malignant.
