J Korean Soc Emerg Med.  2011 Apr;22(2):178-180.

A Patient with Altered Mental Status During Taking Fluconazole

Affiliations
  • 1Department of Emergency Medicine, College of Medicine, Kangwon National University Hospital, Kangwon National University, Chuncheon, Korea. cjhemd@kangwon.ac.kr
  • 2Department of Internal Medicine, College of Medicine, Kangwon National University Hospital, Kangwon National University, Chuncheon, Korea.

Abstract

Fluconazole is a fungistatic agent that is used for treating systemic and superficial fungal infections like onychomycosis and tinea pedis. Various adverse effects of fluconazole have been reported regardless of the total dosage and the duration of treatment. We consider the number of patients who visit the emergency room with nonspecific symptoms that are related to antifungal agents are not inconsiderable. In this case, 44-year-old male patient experienced mental change during taking fluconazole to treat tinea pedis. The understanding of the side effects and the drug interactions with antifungal agents like fluconazole can help to treat patients with nonspecific symptoms that are related to antifungal agents.

Keyword

Fluconazole; Adverse effects; Hyperammonemia; Consciousness

MeSH Terms

Adult
Antifungal Agents
Consciousness
Drug Interactions
Emergencies
Fluconazole
Humans
Hyperammonemia
Male
Onychomycosis
Tinea
Tinea Pedis
Antifungal Agents
Fluconazole
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