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External Validation of a Pharmacokinetic Model of Propofol for Target-Controlled Infusion in Children under Two Years Old

Ji SH, Lee JH, Cho JY, Kim HS, Jang YE, Kim EH, Kim JT, Kim HS

BACKGROUND: Previously, a linked pharmacokinetic-pharmacodynamic model (the Kim model) of propofol with concurrent infusion of remifentanil was developed for children aged 2–12 years. There are few options for pharmacokinetic-pharmacodynamic model...
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Updates on the Sedation for Gastrointestinal Endoscopy

Lee JK, Lee YJ, Cho JH, Im JP, Park CH, Jang JY, Jang BI, the Quality Management Committee and the Disinfection Management/Conscious Sedation Committee of Korean Society of Gastrointestinal Endoscopy (KSGE)

Sedation, defined as the depressed level of consciousness, induced by drug administration, is widely used for gastrointestinal endoscopy to relieve a patient’s anxiety and discomfort. In addition, successful procedure is...
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Case Series: Successful Resuscitation of Severe Facial Injuries Caused by a Chainsaw

Choi HJ

The treatment outcome remains poor of severe facial injuries because of the high risk of compromised airway or massive bleeding. We experienced two successful treatment cases of severe facial injury...
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Distinct Topographical Patterns of Spike-Wave Discharge in Transgenic and Pharmacologically Induced Absence Seizure Models

Lee S, Hwang E, Lee M, Choi JH

Absence seizures (AS) are generalized non-convulsive seizures characterized by a brief loss of consciousness and spike-and-wave discharges (SWD) in an electroencephalogram (EEG). A number of animal models have been developed...
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Assessment of phase-lag entropy, a new measure of electroencephalographic signals, for propofol-induced sedation

Jun MR, Yoo JH, Park SY, Na S, Kwon H, Nho JH, Kim SI

BACKGROUND: Phase-lag entropy (PLE) was recently described as a measurement of temporal pattern diversity in the phase relationship between two electroencephalographic signals from prefrontal and frontal montages. This study was...
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Paradoxical Motor and Cognitive Function Recovery in Response to Zolpidem in a Patient with Hypoxic-ischemic Brain Injury: A Case Report

Hahm MH, Woo J

We report an extremely rare case of a patient with hypoxic-ischemic brain injury who recovered consciousness and motor and cognitive functions due to paradoxical response after zolpidem administration. A 32-year-old...
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Effects site concentrations of propofol using target-controlled infusion in dental treatment under deep sedation among different intellectual disability types

Salinas Salmeron KS, Kim HJ, Seo KS

BACKGROUND: We aimed to assess the dose needed to achieve the propofol effect-site concentration using target-controlled infusion in intellectually disabled patients and to detail the most effective method for achieving...
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Influence of Ordering Kiosk Nutrition Information Transparency and Information Quality on the Customer Behavioral Intention in Fast Food Restaurants

Han JH, Oh YH, Ham S

This study examined the perception and behavior of fast food restaurant customers toward ordering kiosk nutrition information. Specifically, the influence of nutrition information transparency and information quality on behavioral intention...
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Factors Affecting the Response to First-Line Treatments in Patients with Anti-N-Methyl-D-Aspartate Receptor Encephalitis

Zhang X, Wang C, Zhu W, Wang B, Liang H, Guo S

BACKGROUND AND PURPOSE: Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is the most common type of autoimmune encephalitis. This study aimed to explore the possible factors affecting the response to first-line treatments in...
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Clinical and neuroimaging determinants of minimally conscious and persistent vegetative states after acute stroke

Kumral E, Bayam FE, Köken B, Erdoğan C

BACKGROUND: Patients with persistent vegetative state (PVS) show no evidence of awareness of self or their environment, and those with minimally conscious state (MCS) have severely impaired consciousness with minimal...
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Nursing Students' Environmental Consciousness and Medical Waste Related Knowledge and Attitudes

Ha JH, Lee HJ

PURPOSE: The purpose of this study is to find out how much influence nursing students' environmental consciousness and knowledge of medical waste have on their attitudes toward medical waste. METHODS: The...
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Anti-Ma2-Associated Encephalitis with Axonal Sensorimotor Polyneuropathy

Song JM, Kwon S, Kim J, Kim BJ, Min JH

Anti-Ma2-associated encephalitis is one of the paraneoplastic limbic and brainstem encephalitis characterized by decreased consciousness, parkinsonism and the limitation of vertical eye movement. It is usually associated with non-small cell...
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Prevention and management of delirium in critically ill adult patients in the intensive care unit: a review based on the 2018 PADIS guidelines

Park SY, Lee HB

Delirium is an acute, confusional state characterized by altered consciousness and a reduced ability to focus, sustain, or shift attention. It is associated with a number of complex underlying medical...
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Comparative Analysis of Phase Lag Entropy and Bispectral Index as Anesthetic Depth Indicators in Patients Undergoing Thyroid Surgery with Nerve Integrity Monitoring

Seo KH, Kim KM, Lee SK, John H, Lee J

BACKGROUND: Most depth of anesthesia (DOA) monitors rely on the temporal characteristics of a single-channel electroencephalogram (EEG) and cannot provide spatial or connectivity information. Phase lag entropy (PLE) reflects DOA...
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Motor Recovery after Seizure Induced by Repetitive Transcranial Magnetic Stimulation

Park J, Kim YS, Ko EJ, Park YG

Despite the low incidence, seizures induced by repetitive transcranial magnetic stimulation (rTMS) have been studied as they may cause neurological and functional regression. Seizures may predict poor outcomes in stroke...
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Diagnosis and Clinical Progress in a Case of Dementia with Lewy Bodies

Lee SS, Kim MJ

Dementia with Lewy bodies(DLB) is the second most common neurodegenerative disease. However, DLB might not be adequately diagnosed due to its variety of clinical symptoms. The authors present 65-year-old Mrs....
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Posterior Reversible Encephalopathy Syndrome in a Patient with Systemic Lupus Erythematosus and Systemic Sclerosis Overlap Syndrome

Song YM

Posterior reversible encephalopathy syndrome (PRES) is characterized by neurotoxic symptoms and neuroimaging finding of reversible cerebral edema in association with various conditions including hypertension, eclampsia, and autoimmune diseases. The author...
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The Effects of Depression on the Survival of Terminal Cancer Patients in a Palliative Care Unit

Son JS, Kim WH, Lee JS, Kim HY, Kang SG, Choi SH, Bae JN

OBJECTIVES: This study examined the association between depression and survival time in terminal cancer patients admitted to the palliative care unit. Emotional problems are important for terminal cancer patients in...
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Understanding and Application of Lucid Dreams in Sleep Medicine

Cyn J

A lucid dream is defined as a dream during which a dreamer is aware that she/he is dreaming. The existence of lucid dream has long been known in the literature,...
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Acute subarachnoid hemorrhage due to giant vertebrobasilar dolichoectasia

Kim JY, Kim JW, Yoon MJ, Suk SH

BACKGROUND: Vertebrobasilar dolichoectasia (VBD) is a dilatative arteriopathy of the vertebrobasilar artery. Subarachnoid hemorrhage (SAH) is a rare but fatal complication of VBD. CASE REPORT: A 65-year-old man was brought to...
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