J Sleep Med.  2016 Jun;13(1):1-7. 10.13078/jsm.16001.

Optimizing the Pharmacological Treatment for Insomnia

  • 1Department of Psychiatry, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. schung@amc.seoul.kr


The Cognitive-Behavioral Therapy for Insomnia (CBT-I) is an important and effective treatment for insomnia patients. However, it is not easy for most general practitioners to learn and practice CBT-I, and it is popular to prescribe sleeping pills to insomnia patients in clinical practice. In the case, we need to consider the factors which can influence the effect of sleeping pills to prescribe sleeping pills appropriately and safely with the lowest dosage. Age, gender, medical or psychiatric comorbid disease, workplace, or sleep environment may affect the patients' satisfaction with their sleeping pills. Physician should know about the mechanism of action of each sleeping pill and which type of sleeping pills needs to be prescribed to patients in each situation. Physician also needs to ask patients what time they took their sleeping pills and check whether patients followed physician's sleeping pills administration instruction or not. In this review, we want to discuss about optimizing the sleeping pills prescription to insomnia patients.


Drug therapy; Hypnotics; Insomnia; Sleep
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