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Age-Limited Effects of Low-Frequency Transcutaneous Electric Nerve Stimulation on Insomnia: A 4-Week Multi-Center, Randomized Controlled Study

Lee HJ, Hong JK, Choi H, Chung S, Yoon IY

Objective Insomnia disorder is a common condition with considerable harmful effects on health. We investigated the therapeutic efficacy and safety of low-frequency transcutaneous electric nerve stimulation (LF-TENS) as an alternative...
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Pharmacotherapy for Insomnia of the Elderly

Kang SG

Insomnia is a common disease in the elderly. It is caused by various etiologies and their combinations. Therefore, treatment should be tailored to the individual. Cognitive-behavioral therapy for insomnia (CBT-I)...
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Discrepancy Between Desired Time in Bed and Desired Total Sleep Time, Insomnia, Depression, and Dysfunctional Beliefs About Sleep Among the General Population

Lee J, Cho IK, Kim K, Kim C, Park CHK, Yi K, Chung S

Objective The aim of this study was to explore the factors that can influence the severity of insomnia in the general population. We also aimed to examine whether sleep effort...
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Effect of Long-Term Benzodiazepines for Chronic Insomnia on Cognitive Function and Waking Electroencephalography: A Case-Control Study

Bang YR, Jeon HJ, Yoon IY

Objective The relationship between benzodiazepine use and cognitive decline in insomnia patients has been reported, but still conflicting. Thus, we tried to determine whether long-term exposure of benzodiazepine might be...
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Mediation Effect of Insomnia Symptoms on Relation Between Stress and Quality of Life

Lee S, Lee HJ, Cho CH

Objective Among various causes of insomnia, stress is the most common and representative cause. Insomnia is also known to negatively affect the quality of life (QoL). The objective of this...
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Association of Sleep Perception With Objective and Subjective Sleep Variables in Insomnia Patients

Yoon G, Oh SM, Seo MC, Lee MH, Yoon SY, Lee YJ

Objectives: Our study aims to investigate the clinical and polysomnographic variables associated with subjective sleep perception. Methods: Among the patients who underwent nocturnal polysomnography (PSG) at the Center for Sleep and...
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Validation of the Thyrotoxicosis-associated Insomnia Model Induced by Thyroxine through Sympathetic Stimulation: Face, Construct and Predictive Perspectives

Ai Z, He H, Wang T, Chen L, Huang C, Chen C, Xu P, Zhu G, Yang M, Song Y, Su D

  • KMID: 2524036
  • Exp Neurobiol.
  • 2021 Dec;30(6):387-400.
  • doi: 10.5607/en21023
Insomnia has become a common central nervous system disease. At present, the pathogenesis of insomnia is not clear. Animal models can help us understand the pathogenesis of the disease and...
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Smartphone Addiction Proneness Is Associated With Subjective-Objective Sleep Discrepancy in Patients With Insomnia Disorder

Lee J, Jung HY, Lee SI, Youn H, Kim SG

Objective Subjective reports of patients with insomnia often show a discrepancy with their objective assessments of sleep. We aimed to assess subjective-objective sleep discrepancy in subjects with insomnia disorder as...
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An update on the cause and treatment of sleep disturbance in children and adolescents with autism spectrum disorder

Seo WS

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by abnormalities in social communication/interaction and restrictive, repetitive patterns of behavior. ASD is a relatively common psychiatric disorder, with a prevalence...
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Understanding insomnia as systemic disease

Yun S, Jo S

Sleep plays a critical role in homeostasis of the body and mind. Insomnia is a disease that causes disturbances in the initiation and maintenance of sleep. Insomnia is known to...
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Effects and mechanisms of a mindfulness-based intervention on insomnia

Kim HG

Medication alone is not sufficient to treat insomnia. In addition, the side effects of sleep medications themselves cannot be ignored during treatment. Insomnia begins with poor sleep quality and discomfort,...
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Smartphone Screen Time Among University Students in Lebanon and Its Association With Insomnia, Bedtime Procrastination, and Body Mass Index During the COVID-19 Pandemic: A Cross-Sectional Study

Hammoudi SF, Mreydem HW, Ali BTA, Saleh NO, Chung S, Hallit S, Salameh P

Objective We aimed to investigate the association of increased smartphone screen time with insomnia, bedtime procrastination, depression, anxiety, body mass index (BMI), and physical activity during the coronavirus disease of...
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Associations between Sleep and Work-Related Cognitive and Emotional Functioning in Police Employees

Sørengaard TA, Olsen A, Langvik E, Saksvik-Lehouillier I

Aim We aimed to examine the cross-sectional and longitudinal associations between sleep and work-related impaired cognitive and emotional functioning in police employees. Methods This study included 410 participants (52% men) employed in a...
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Insomnia, Anxiety, and Depression in Patients First Diagnosed With Female Cancer

Ho D, Kim SY, Kim SI, Kim SY, Lim WJ

Objective This study evaluated whether insomnia, anxiety, and depression differ by type of gynecological or breast cancer. Methods From September 7, 2011, to July 14, 2015, this study included 232 patients...
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Depression, Rather Than Cancer-Related Fatigue or Insomnia, Decreased the Quality of Life of Cancer Patients

Yeo S, Lee J, Kim K, Kim HJ, Chung S

Purpose Cancer-related fatigue is a common and distressing symptom that occurs during cancer treatment. This study aimed to find factors that are related to cancer-related fatigue, and its effect on...
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Brain Metabolite Changes in Insomnia and Obstructive Sleep Apnea

Hong H, Lee H, Yoon S, Kim J

Sleep is essential to brain function and mental health. Insomnia and obstructive sleep apnea (OSA) are the two most common sleep disorders, and are major public health concerns. Proton magnetic...
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Mindfulness-Based Therapy for Insomnia

Lee HY

Sleep disturbance is a common health complaint affecting an estimated 10-25% of the general population. Pharmacotherapy is a traditional treatment and cognitive behavioral therapy is well demonstrated as an efficacious...
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Clinical Application of Digital Therapeutics for Insomnia

Cho CH

Insomnia is one of the most common sleep disorders experienced by modern people, and treatment is often not adequate due to various limitations. Digital therapeutics for insomnia are expected to...
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Neuromodulation for Insomnia Management

Yoon HK

Hyperarousal or increased brain excitability is thought to play a key role in the pathophysiology of insomnia. Neuromodulation techniques are emergent complementary therapies for insomnia and can improve sleep by...
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Zolpidem-Induced Complex Sleep-Related Behavior

Lee J, Chang SM

  • KMID: 2517217
  • J Korean Soc Biol Ther Psychiatry.
  • 2021 Jun;27(2):89-96.
Zolpidem is a non-benzodiazepine hypnotic agent as an agonist of the GABA A benzodiazepine receptor. Zolpidem is considered to have lower abuse and dependence potential than benzodiazepines, and is widely...
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