J Korean Acad Rehabil Med.  1998 Oct;22(5):1013-1020.

Magnetic Resonance Findings in Cerebral Palsy and a Correlation with Developmental Disabilities

• Park CI
• Park ES
• Shin JC
• Kim SW
• Bang IK

Abstract

OBJECTIVE
To investigate the correlation between magnetic resonance imaging (MRI) findings for children with cerebral palsy (CP) and the severity of their developmental disability. METHOD: MRI and M nchener Funktionelle Entwicklungs Diagnostik (MFED) were used for the evaluation of 52 children with CP. MFED quotient (MFED age/corrected age 100) was compared to the MRI findings.
RESULTS
Of the 52 MRIs, no abnormalities were found in 7 cases (13%), periventricular leukomalacias (PVLs) in 37 cases (71.2%), corpus callosum abnormalities in 33 cases (63.5%), delayed myelinations in 8 cases (15.4%), congenital brain abnormalities in 6 cases (11.5%), and central sulcus abnormalities in 3 cases (5.8%). Among 27 patients who were born preterm, the major MRI finding was PVL (100%), indicative of a hypoxic brain injury. All patients with a normal MRI were born at term. There were significant correlations between the MFED quotient and the severity of PVL. The ratio of corpus callosum length/brain anteroposterior diameter was correlated with a developmental disability.
CONCLUSION
MRI findings for the patients with CP are well correlated with the developmental disabilities and the timing of brain insult.

Keyword

Cerebral palsy; Brain MRI; M nchener Funktionelle Entwicklungs Diagnostik; Developmental disability

MeSH Terms

Brain
Brain Injuries
Cerebral Palsy*
Child
Corpus Callosum
Developmental Disabilities*
Humans
Infant, Newborn
Leukomalacia, Periventricular
Magnetic Resonance Imaging
Myelin Sheath