J Korean Soc Radiol.  2011 Sep;65(3):285-288.

Tubulocystic Carcinoma of the Kidney with Bone Metastasis: A Case Report

• Im MH
• Jung YY
• Kim EK
• Yoo TK
• Choi YS
• Kim YJ

Abstract

Tubulocystic carcinoma of the kidney is a rare neoplasm occurring predominantly in males, and has a relatively indolent disease course. Herein, we present a case of histologically proven tubulocystic renal carcinoma in a 22-year-old woman with emphasis on the imaging findings of CT, US, 18-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (18F-FDG PET/CT), and pathological features. Unusually, the woman had single bone metastasis in the left parasymphyseal pubic bone without any other evidence of metastatic disease on 18F-FDG PET/CT at the time of the diagnosis. A few months later, the bone metastases progressed into multiple cervical vertebrae and the skull base.

MeSH Terms

Carcinoma, Renal Cell
Cervical Vertebrae
Electrons
Female
Fluorodeoxyglucose F18
Humans
Kidney
Kidney Neoplasms
Male
Neoplasm Metastasis
Pubic Bone
Skull Base
Young Adult
Fluorodeoxyglucose F18

Figure

• 

  Fig. 1 Tubulocystic carcinoma of the right kidney and left parasymphyeal pubic bone metastasis in a 22-year-old woman. A, B. Contrast-enhanced axial and coronal reformatted CT images show a 6.4 cm sized well-defined multilocular cystic mass (arrow) with enhancing septa, multifocal curvilinear calcifications, and solid portions in the lower pole of the right kidney. C. Contrast-enhanced axial CT image shows an osteolytic lesion (arrowhead) with soft tissue formation in the left parasymphyseal pubic bone. D, E. Gray-scale and color Doppler US images showed a lobulating multiseptated heterogeneous cystic mass with solid portions (arrows) and calcifications (arrowheads), which showed some inner vascularity in the lower pole of the right kidney. F, G. Coronal 18F-FDG PET/CT images show peripheral intense FDG uptake with central photon defect in the lower pole of the right kidney (arrow), and another intense FDG uptake in the left parasymphyseal pubic bone (arrowhead). H. The tumor is a well circumscribed, multilocular cystic and solid mass with a spongy appearance, measuring 11.3 × 10.0 × 6.5 cm on gross specimen. I. Photomicrograph showed varying sized cysts and well-formed tubules (Hematoxylin & Eosin stain, × 40). The epithelial cells have abundant eosinophilic cytoplasm and prominent nucleoli (Inserted box, × 200). Note.-18F-FDG PET/CT = 18-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography

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