J Korean Soc Radiol.  2018 Oct;79(4):237-241. 10.3348/jksr.2018.79.4.237.

Palliative Transcatheter Arterial Chemoembolization for Relieving Metastatic Bone Pain due to Hepatocellular Carcinoma: A Case Report

Affiliations
  • 1Department of Radiology, Wonkwang University School of Medicine & Hospital, Iksan, Korea. msnrage23@naver.com
  • 2Department of Radiology, Yeonggwang Medical Center, Yeonggwang, Korea.

Abstract

Bone metastasis is the third most common extrahepatic metastasis from hepatocellular carcinoma (HCC), following lung and lymph node metastasis. Although transcatheter arterial chemoembolization (TACE) is widely used for the treatment for unresectable HCC in the liver, its effects on bone metastasis from HCC have not been well described in past literature. We report a case of a patient with a metastatic bone lesion from an HCC treated with TACE. After the procedure, the patient's pain and narcotic requirement significantly decreased without major complications.


MeSH Terms

Bone Neoplasms
Carcinoma, Hepatocellular*
Chemoembolization, Therapeutic
Humans
Liver
Lung
Lymph Nodes
Neoplasm Metastasis

Figure

  • Fig. 1 TACE of symptomatic bone metastasis from hepatocellular carcinoma in a 66-year-old man. A-C. In the selective arteriogram of the right intercostobronchial trunk (A), right 3rd (B), 4th and 5th (C) intercostal arteries, tumoral staining that correspond to the bone metastasis are seen. D. Completion angiogram after TACE using chemomixure of Adriamycin and lipiodol and gelfoam particle reveals > 75% reduction of tumor blush, which means technical success. TACE = transcatheter arterial chemoembolization TACE of symptomatic bone metastasis from hepatocellular carcinoma in a 66-year-old man. E. On follow-up CT after 3 months of TACE (right), size of the mass narrowing T3 spinal canal decreases and marginal shape of the mass changes to concave compared to CT before TACE (left). TACE = transcatheter arterial chemoembolization

  • Fig. 2 Total number of medication decreased with improved patient's pain after TACE as depicted in this graph. TACE = transcatheter arterial chemoembolization


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