Korean J Psychosom Med.  2016 Jun;24(1):20-27. 10.0000/kjpm.2016.24.1.20.

Pharmacological Treatments of Headache

  • 1Department of Psychiatry, Chonbuk National University Medical School, Jeonju, Korea. yangjc@jbnu.ac.kr
  • 2Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National Universtiy Hospital, Jeonju, Korea.


Headache is one of the most common physical symptoms which almost everyone experience at least once during a life. Headache is often associated with disability, but rarely with secondary headache which could result in a serious life-threatening illness, i.e. brain tumor. However, in most cases, headache is a benign illness which comprises a primary headache, i.e. migraine or tension-type headache. The accurate diagnosis of headache is critical for clinicians and it begins with history taking and physical examination since there are no diagnostic tests for primary headaches. Nowadays, there are a wide variety of pharmacological treatments according to each headache disorder. The specific purposes of this review are introducing history of classification of headache disorder and presenting diagnostic process of headache disorder. Then, we discuss the effective pharmacological treatment strategies of each headache disorder.


Headache; Diagnosis; Pharmacological treatment
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