Korean J Urol.  2008 Feb;49(2):122-126.

A Protocol for Transrectal, Ultrasonography-guided, 41-core Prostate Needle Biopsy

• Jeon SB
• Zhao C
• Jung YB
• Park YK
• Park JK

Abstract

PURPOSE
We evaluated the rate of prostate cancer detection using the transrectal ultrasound(TRUS) guided, 41-core prostate needle biopsy protocol. MATERIALS AND METHODS: Between May 2006 and May 2007, 110 patients received a 12-core prostate needle biopsy(Group I) and 62 patients underwent a 41-core prostate needle biopsy(Group II) under local anesthesia. In addition to sextant biopsy, 41-core prostate needle biopsies were obtained from the each lateral peripheral zone(base, mid, and apex glands), midline peripheral zone(base, mid, and apex glands) and each transition zone. RESULTS: There were no significant differences between the two groups for age, prostate-specific antigen(PSA), or prostate volume. The cancer detection rate in the Group I and Group II was 19.1% and 24.2%, respectively. We found a significantly higher detection rate in the 41-core biopsy with prostate volumes of more than 40cc(28.1% vs 11.3%). The intraoperative pain score was lower in Group II than Group I(1.57+/-1.45 vs 3.17+/-1.73, p<.01). CONCLUSIONS: The 41-core prostate needle biopsy protocol is safe and intraoperative pain is low. The cancer detection rate of the 41-core prostate needle biopsy was higher than the 12-core prostate needle biopsy in patients with a prostate volume of more than 40cc.

Keyword

Prostate cancer; Biopsy

MeSH Terms

Anesthesia, Local
Biopsy
Biopsy, Needle
Humans
Needles
Prostate
Prostatic Neoplasms

Figure

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  Fig. 1 Location of biopsies in the 41-core procedure. A dark circle (sextant and far lateral peripheral zones) means three biopsies performed from the same site. A gray circle means biopsies at the midline peripheral zones and an open circle means biopsies performed in both transition zones.

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