Korean J Med.  1999 Feb;56(2):235-239.

A Case of CD5 Negative B-Cell Chronic Lymphocytic Leukemia

Affiliations
  • 1Department of Internal Medicine, Pusan Veterans Hospital, Korea.
  • 2Department of Clinical Pathology, Pusan Veterans Hospital, Korea.
  • 3Department of Anatomical Pathology, Pusan Veterans Hospital, Korea.
  • 4Department of Clinical Patholog Pusan Paik hospital, College of Medicine, In Je University, Pusan, Korea.

Abstract

A 67-year-old male visited Pusan Veterans Hospital due to general weakness and weight loss for 6 months. Physical examination showed non-tender 4 finger breaths sized splenomegaly and both inguinal and cervical lymphadenopathy. The white blood cell count was 25,300/uL with 91% morphologically mature lymphocytes. Bone marrow aspirate revealed hypercellularity with 74.5% lymphocytes morphologically similar to peripheral lymphocytes. The immunophenotpying study of lymphocytes displayed the phenotype of CD19(+), CD20(+), HLA-DR(+), sIg(+) but CD5(-). We concluded that this patients's diagnosis is CD 5 negative B-cell chronic lymphocytic leukemia.

Keyword

CD5 negative; B-cell Chronic Lymphocytic Leukemia

MeSH Terms

Aged
B-Lymphocytes*
Bone Marrow
Busan
Diagnosis
Fingers
Hospitals, Veterans
Humans
Leukemia, Lymphocytic, Chronic, B-Cell*
Leukocyte Count
Lymphatic Diseases
Lymphocytes
Male
Phenotype
Physical Examination
Splenomegaly
Weight Loss
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