Korean J Gastrointest Endosc.  2009 Jul;39(1):42-45.

A Case of a Duodenal Gastrointestinal Stromal Tumor with a Bleeding Ulcer

Affiliations
  • 1Department of Internal Medicine, Kwandong University College of Medicine, Goyang, Korea. chg21@kd.ac.kr
  • 2Department of Surgery, Kwandong University College of Medicine, Goyang, Korea.
  • 3Department of Pathology, Kwandong University College of Medicine, Goyang, Korea.

Abstract

Duodenal gastrointestinal stromal tumors (GISTs) are relatively rare tumors that commonly present with gastrointestinal bleeding. Evaluation with endoscopic ultrasonography (EUS) is a useful technique for the differential diagnosis of GISTs from other submucosal tumors. A 58-year-old man presented with melena and anemia. An esophago-gastroduodenoscopy showed the presence of a submucosal tumor in the second portion of the duodenum with central ulceration and a flat spot. EUS showed the presence of a suspicious malignant GIST that originated from the proper muscle layer, which was successfully resected. We report a case of a duodenal GIST with a bleeding ulcer. Positive reactivity for CD117 and S-100 was demonstrated by immunohistochemical staining.

Keyword

Gastrointestinal stromal tumors; Duodenum; Hemorrhage; Endosonography

MeSH Terms

Anemia
Diagnosis, Differential
Duodenum
Endosonography
Gastrointestinal Stromal Tumors
Hemorrhage
Humans
Melena
Middle Aged
Muscles
Ulcer
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