Korean J Gastroenterol.  1999 Jul;34(1):125-130.

A Case of Acute Dilated Cardiomyopathy Caused by Coxsackie Virus B in a Patient with Crohn's Disease

• Kwon CI
• Hong SP
• Choi YJ
• Hwang KH
• Oh J
• Kim KC
• Hwang SG
• Park PW
• Rim KS

Abstract

A 23-year-old man was admitted for watery diarrhea, abdominal pain and fever. He had received an operation for an anal fistula at a private clinic about 3 years ago. Recently, he was treated under the diagnosis of tuberculosis colitis for about 15 months at another hospital, but showed no improvement. He lost 30 kg of weight for last 18 months. On admission, he was 178 cm high and weighed 50 kg. He had a pararectal abscess and a fistula between terminal ileum and sigmoid colon. He was diagnosed as Crohn's disease. After taking 2 weeks of medications composed with sulfasalazine, corticosteroid, 6-mercaptopurine and antibiotics, his condition improved rapidly and gained 5 kg of weight. On the 6th hospital week, he complained of dyspnea on exertion and orthopnea. His chest X-ray revealed a marked cardiomegaly, while his heart was normal in size and shape. He was diagnosed as dilated cardiomyopathy caused by coxsackie virus B, which was confirmed by serologic test. He died at the 46th hospital day. We report this case with a review of literature.

Keyword

Crohn's disease; Dilated cardiomyopathy; Coxsackie virus

MeSH Terms

6-Mercaptopurine
Abdominal Pain
Abscess
Anti-Bacterial Agents
Cardiomegaly
Cardiomyopathy, Dilated*
Colitis
Colon, Sigmoid
Crohn Disease*
Diagnosis
Diarrhea
Dyspnea
Fever
Fistula
Heart
Humans
Ileum
Rectal Fistula
Serologic Tests
Sulfasalazine
Thorax
Tuberculosis
Young Adult
6-Mercaptopurine
Anti-Bacterial Agents
Sulfasalazine