Korean J Dermatol.  1998 Oct;36(5):962-964.

A Case of Linear IgA Bullous Dermatosis

• Jeong SW
• Lee SW
• Cha SH
• Park SD

Abstract

We describe an 18-year-old male with generalized pruritic, tense annular or polycyalic blistera on normal-appearing skin or erythematous bases. Histopathological fmdings of an iatact early blistering showed subepidermal blistering and papillary neutrophilic gnicroabscesses. A direct immunofluctescent study of a section from the skin adjacent to a lesioti revealed linear deposits of IgA at the dermoepidermal junction. There were no deposits of IgG, lgM, or C3. In 1.0M NaC1 eplit skin, IgA was found to be bound linearly on the epidermal roof. The patient respmded weIl to eteroid and dapsone therapy.

MeSH Terms

Adolescent
Blister
Dapsone
Humans
Immunoglobulin A
Immunoglobulin G
Linear IgA Bullous Dermatosis*
Male
Neutrophils
Skin
Transcutaneous Electric Nerve Stimulation
Dapsone
Immunoglobulin A
Immunoglobulin G