Korean J Dermatol.  2000 Aug;38(8):1150-1153.

A Case of Primary Nodular Cutaneous Amyloidosis

Affiliations
  • 1Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.

Abstract

Primary nodular cutaneous amyloidosis is a very rare type of amyloidosis, it must excluded the secondary nodular deposition of systemic amyloidosis. We report herein 47-year-old male with a erythematous waxy nodule on his parietal scalp for one year. Histopathologic examination showed homogenous amorphous eosinophilic deposition in the dermis with nodular fashion. In Congo red, amyloid material stained positively and showed apple-green birefringence with polarized light. On electron microscopic examination, extensive deposit of amyloid with typical 6-10 nm filament was confirmed. He had neither clinical nor laboratory evidence of systemic amyloidosis. We reviewed previously reported nodular amyloidosis in Korea.

Keyword

Nodular amyloidosis

MeSH Terms

Amyloid
Amyloidosis*
Birefringence
Congo Red
Dermis
Eosinophils
Humans
Korea
Male
Middle Aged
Rabeprazole
Scalp
Amyloid
Congo Red
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