Korean J Dermatol.
2005 Jun;43(6):812-817.
Two Cases of Classic Polyarteritis Nodosa with Multiple Aneurysmal Ruptures
- Affiliations
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- 1Department of Dermatology, Cheju National University, College of Medicine, Jeju, Korea. rulidroxim@hanmail.net
- 2Department of Urology, Cheju National University, College of Medicine, Jeju, Korea.
Abstract
- Classic polyarteritis nodosa (PAN) is a systemic segmental necrotizing vasculitis which shows transmural fibrinoid necrosis with surrounding inflammation in small to medium-sized muscular arteries, preferentially at vessel bifurcations, resulting in microaneurysm formation. Classic PAN commonly affects the kidney, liver, muscle, nerve, gastrointestinal tract and heart. Arteriography demonstrates microaneurysm or occlusion of the visceral arteries in 90% of the patients with classic PAN. However, rupture of the hepatic or renal artery aneurysm is uncommon cascade. We report two exceptional cases who presented with aneurysmal ruptures of the hepatic or renal artery and visceral infarction.
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