Korean J Dermatol.  2006 Jan;44(1):97-99.

A Case of Anagen Effluvium Induced by INH (Isonicotinic Acid Hydrazide)

Affiliations
  • 1Department of Dermatology, College of Medicine, Eulji University, Seoul, Korea. nicos@korea.com
  • 2Department of Internal Medicine, College of Medicine, Eulji University, Seoul, Korea.

Abstract

We report a case of a 30 year-old woman who presented with acute scalp hair loss induced by isonicotinic acid hydrazide gap (INH). Considerable hair loss started within 4 weeks of INH administration. There was no evidence of dermatitis, allergic reaction, or any other cause for the hair loss. INH was discontinued, and the hair loss stopped within 4 weeks, with new hair growth seen. There was complete recovery of hair loss after 12 weeks of alopecia. Medication-induced hair loss is an occasional adverse effect of many drugs, however hair loss induced by INH has been reported in only 1 case. The complete recovery from anagen effluvium is difficult to explain, but it could have been due to the early discontinuance of INH.

Keyword

Anagen effluvium; Isonicotinic acid hydrazide

MeSH Terms

Adult
Alopecia
Dermatitis
Female
Hair
Humans
Hypersensitivity
Isoniazid
Scalp
Isoniazid
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