Korean J Dermatol.  2007 May;45(5):496-502.

Bullous Erythema Multiforme and Stevens-Johnson Syndrome Caused by Mycoplasma pneumoniae Infection

  • 1Department of Dermatology, College of Medicine, Cheju National University, Jeju, Korea. rulid@cheju.ac.kr
  • 2Department of Pediatrics, College of Medicine, Cheju National University, Jeju, Korea.


In adults, bullous erythema multiforme is most often caused by herpes simplex virus infection, while Stevens-Johnson syndrome is most often associated with drug hypersensitivity. Mycoplasma pneumoniae infection is highly known to be a cause of bullous erythema multiforme and Stevens-Johnson syndrome in children and young adults. To our knowledge, there are only a few reports of bullous erythema multiforme or Stevens-Johnson syndrome induced by M. pneumoniae infection in the Korean literature. We encountered two cases of female children diagnosed as having bullous erythema multiforme associated with M. pneumoniae infection. We also describe an unusual case of Stevens-Johnson syndrome associated with M. pneumoniae infection in a 65-year-old woman.


Bullous erythema multiforme; Mycoplasma pneumoniae infection; Stevens-Johnson syndrome
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