Infect Chemother.  2008 Dec;40(6):327-329. 10.3947/ic.2008.40.6.327.

A Case of Stevens-Johnson Syndrome Associated with Mycoplasma pneumoniae Pneumonia in an Adult Patient

Affiliations
  • 1Department of Internal Medicine, Gachon University, Gil Medical Center, Incheon, Korea. yspark@gilhospital.com
  • 2Department of Laboratory Medicine, Gachon University, Gil Medical Center, Incheon, Korea.

Abstract

Stevens-Johnson syndrome is an acute mucocutaneous syndrome that is related to drugs and infections. Mycoplasma pneumoniae infection is known as one of the causes of Stevens-Johnson syndrome in children and young adults. In Korea, Mycoplasma pneumoniae infection is rarely reported as a cause of Stevens-Johnson syndrome in adults. We report a case of Stevens-Johnson syndrome associated with Mycoplasma pneumoniae pneumonia in an adult patient. A 34-years old woman was admitted to our hospital and was diagnosed with mycoplasma pneumonia. At the time of admission, she had hemorrhagic crusts on her lips. On the 2nd day of admission, target lesions also developed on her skin. We diagnosed her disease as Stevens-Johnson syndrome associated with Mycoplasma pneumoniae pneumonia. She completely recovered from pneumonia and Stevens-Johnson syndrome after treatment with antibiotics and conservative management.

Keyword

Stevens-Johnson syndrome; Mycoplasma pneumoniae

MeSH Terms

Adult
Anti-Bacterial Agents
Child
Female
Glycogen Storage Disease Type VI
Humans
Korea
Lip
Mycoplasma
Mycoplasma pneumoniae
Pneumonia
Pneumonia, Mycoplasma
Skin
Stevens-Johnson Syndrome
Young Adult
Anti-Bacterial Agents

Figure

  • Figure 1 Picture A shows hemorrhagic crust on the lips. Picture B shows target lesions on both soles. Picture C shows target lesions on both knees.

  • Figure 2 High-resolution computed tomography showing patchy consolidation in right lower lobe.


Reference

1. Ludlam GB, Bridges JB. Association of Stevens-Johnson syndrome with antibody for Mycoplasma pneumoniae. Lancet. 1964. 1:958–959.
2. Kim JW, Kim YW. Bullous Erythema Multiforme and Stevens-Johnson Syndrome Caused by Mycoplasma pneumoniae Infection. Korean J Dermatol. 2007. 45:496–502.
3. Hebra F. Atlas der Hautkrankheiten. 1866. Vienna: Kaiserliche Akademie der Wissenchaften Wien.
4. Stevens AM, Johnson FC. A new eruptive fever associated with stomatitis and ophthalmia. Am J Dis Child. 1922. 24:526–533.
Article
5. Shin HT, Chang MW. Drug eruptions in children. Curr Probl Pediatr. 2001. 31:207–234.
Article
6. Dinerman M. Stevens-Johnson syndrome with mycoplasma pneumoniae and enterovirus. Int Pediat. 2004. 19:237–239.
7. Kroonen LM. Erythema multiforme: case report and discussion. J Am Board Fam Pract. 1998. 11:63–65.
Article
8. Tay YK, Huff JC, Weston WL. Mycoplasma pneumoniae infection is associated with Stevens-Johnson syndrome, not erythema multiforme (von Hebra). J Am Acad Dermatol. 1996. 35:757–760.
Article
9. Modesto Alapont M, Reyes Calzada S, Calabuig Muñoz E, Nauffal Manzur D. Stevens-Johnson syndrome associated with atypical pneumonia. Arch Bronconeumol. 2003. 39:373–375.
10. Lam NS, Yang YH, Wang LC, Lin YT, Chiang BL. Clinical characteristics of childhood erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis in Taiwanese children. J Microbiol Immunol Infect. 2004. 37:366–370.
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