J Korean Soc Traumatol.  2013 Sep;26(3):81-88.

Serologic Markers of Excessive Callus formation in Traumatic Brain Injury Patient

Affiliations
  • 1Department of Orthopedic Surgery, Dankook University Hospital, Chon-an, Korea. mute360@naver.com

Abstract

PURPOSE
Among patients with multiple traumatic fractures, a tendency to form more callus exists in groups with multiple fractures combined with traumatic brain injury. This retrospective study evaluated the hematologic factors that might be useful to predict callus formation by comparing serologic tests and clinical and radiologic results in two groups.
METHODS
From January 2000 to December 2010, patients with femur shaft fractures were divided in two groups: one without traumatic brain injury (control group: 32 cases), and the other with traumatic brain injury (study group: 44 cases). We evaluated routine serologic exams and the amount of callus formation during the follow-up period.
RESULTS
Only the alkaline phosphatase level was statistically different between the two groups, not the White blood cell count, C-reactive protein, total calcium, and lactate dehydrogenase level. The amount of callus formation on the antero-posterior radiograph at the last follow up period was 74.9% in the study group and 42.1% in the control group. Then lateral radiograph showed 73.2% callus formation rate in the study group and 31.8% in the control group.
CONCLUSION
In routine serologic exams, the two groups had no significant differences, except for the alkaline phosphatase level. The group with traumatic brain injury had much more callus formation, but there was no reliable factor to predict callus formation on the routine serologic exam.

Keyword

Traumatic brain injury; Callus formation; Alkaline phosphatase; Fracture healing

MeSH Terms

Alkaline Phosphatase
Bony Callus*
Brain Injuries*
C-Reactive Protein
Calcium
Femur
Follow-Up Studies
Fracture Healing
Humans
L-Lactate Dehydrogenase
Leukocyte Count
Retrospective Studies
Serologic Tests
Alkaline Phosphatase
C-Reactive Protein
Calcium
L-Lactate Dehydrogenase
Full Text Links
  • JKST
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr