J Korean Acad Fam Med.
2006 Dec;27(12):1013-1017.
Development of Liver Cirrhosis in a Elderly Healthy Hepatitis B Carrier with Rheumatoid Arthritis Treated with Low-dose Methotrexate (MTX)
- Affiliations
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- 1Department of Family Medicine and Community Health, Ajou University College of Medicine, Suwon, Korea. mdoc@nate.com
Abstract
- Methotrexate (MTX) is the most widely used slow-acting anti-rheumatic agent in the treatment of rheumatoid arthritis. But, long-term administration of MTX can be complicated with liver fibrosis and even cirrhosis. We report the case in elderly woman with healthy Hepatitis B viral carrier patient who developed liver cirrhosis without viral replication after low-dose MTX therapy for rheumatoid arthritis.
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